Evidence map›Paper›PMID 31127669›Full record

ArticleJournal of veterinary internal medicine2019

Evidence for vertical transmission of Mycoplasma haemocanis, but not Ehrlichia ewingii, in a dog.

Erin Lashnits, Sandra Grant, Brittany Thomas, Barbara Qurollo, Edward B Breitschwerdt

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of veterinary internal medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Unveiling the diversity of hemoplasmas (hemotropic Mycoplasma spp.) in Brazilian wildlife: two decades of molecular discoveries - a scoping review.Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria · 2026
    Article
  4. Molecular analysis of vector-borne pathogens in red foxes (International journal for parasitology. Parasites and wildlife · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Molecular Survey of HemotropicPathogens (Basel, Switzerland) · 2023
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Erin LashnitsComparative Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina.ORCID https://orcid.org/0000-0003-0949-5698
Sandra GrantLake Wheeler Veterinary Hospital, Veterinary Services Department, Raleigh, North Carolina.
Brittany ThomasVector Borne Disease Diagnostic Laboratory, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina.
Barbara QurolloVector Borne Disease Diagnostic Laboratory, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina.ORCID https://orcid.org/0000-0002-9849-2511
Edward B BreitschwerdtVector Borne Disease Diagnostic Laboratory, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina.ORCID https://orcid.org/0000-0002-3506-0279
North Carolina State University · USWheeling Hospital · US

Funding

Comparative Medicine and Translational Research Training ProgramT32OD011130 · OD · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI Lauren Virginia Schnabel · 2012 to 2026
$7.8M
National Institutes of Health Comparative Medicine and Translational Research Program T32OD011130NIH HHS T32 OD011130North Carolina State University
6 · The paper itself

Abstract

A 2-year-old female intact pregnant Beagle was evaluated after the owner surrendered her to a shelter. Prepartum and 2 months postpartum at the time of routine spay, the dam was whole-blood polymerase chain reaction (PCR) positive for Ehrlichia ewingii. She was also whole-blood PCR positive for Mycoplasma haemocanis prepartum and continuously for 5 months thereafter. The dam delivered 5 healthy puppies, 1 of which was whole-blood PCR positive for M. haemocanis. All 5 puppies had antibodies against Ehrlichia spp. at 1 month of age but not thereafter, and all puppies were Ehrlichia spp. PCR negative for 5 months of follow-up. Therefore, this study supports a potential role for vertical transmission in the maintenance of M. haemocanis in dogs as reservoir hosts. In contrast, in this case there was no evidence that E. ewingii was transmitted transplacentally or during the perinatal period.

Indexed as

Dog DiseasesInfectious Disease Transmission, VerticalMycoplasma InfectionsAnimalsAntibodies, BacterialCoinfectionDogsEhrlichiaEhrlichiosisFemaleMycoplasmaPregnancyAntibodies, Bacterialbacterial specieshemotropic mycoplasmaperinatalrickettsiavector-borne

Identifiers

PMID31127669
PMCPMC6639480
OpenAlexW2946779914

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.