Article in Methods in molecular biology (Clifton, N.J.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.8field-weighted citation impact, top 11% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
2 citing papers in PubMed, 4 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
4 authors at 3 institutions in 1 country.
Elise FouquerelDepartment of Biochemistry and Molecular Biology, Thomas Jefferson University, Philadelphia, PA, USA.
Ryan P BarnesDepartment of Environmental and Occupational Health, UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USA.
Hong WangDepartment of Physics, North Carolina State University, Raleigh, NC, USA.
Patricia L OpreskoDepartment of Environmental and Occupational Health, UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USA. plo4@pitt.edu.
UPMC Hillman Cancer Center · USNorth Carolina State University · USThomas Jefferson University · US
Funding
Translational Research Support CoreP30ES025128 · NIEHS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI Hong Wang · 2015 to 2026
$18.3M
Mechanisms of Telomere Resistance to DNA Lesion RemovalR01ES022944 · NIEHS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI OPRESKO, PATRICIA L · 2013 to 2017
$1.6M
ROS driven mitochondrial-telomere dysfunction during environmental stressR33ES025606 · NIEHS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI OPRESKO, PATRICIA L, VAN HOUTEN, BENNETT · 2017 to 2019
$1.6M
Mechanism of protein-mediated looping in a complex environmentR01GM107559 · NIGMS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI RIEHN, ROBERT, WANG, HONG · 2014 to 2017
$1.3M
Sequence and Structure Specific DNA Binding by Cohesin and Genome StabilityR01GM123246 · NIGMS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI WANG, HONG · 2018 to 2021
$1.2M
Inhibition of telomere maintenance by oxidized DNA precursorR01ES028242 · NIEHS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI OPRESKO, PATRICIA L · 2017 to 2018
$722k
ROS driven mitochondrial-telomere dysfunction during environmental stressR21ES025606 · NIEHS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI OPRESKO, PATRICIA L, VAN HOUTEN, BENNETT · 2015 to 2016
$414k
Rotational Tracking of Single Nanoplasmonic Upconverting Nanoparticle-Conjugated Proteins on DNAR21ES027641 · NIEHS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI LIM, SHUANG FANG · 2017 to 2018
$385k
Deciphering the mechanisms of PARP1 activity in telomere integrityK99ES027028 · NIEHS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FOUQUEREL, ELISE · 2016 to 2017
Telomere repeats at chromosomal ends are essential for genome stability and sustained cellular proliferation but are susceptible to DNA damage. Repair of damage at telomeres is influenced by numerous factors including telomeric binding proteins, sequence and structure. Ultraviolet (UV) light irradiation induces DNA photoproducts at telomeres that can interfere with telomere maintenance. Here we describe a highly sensitive method for quantifying the formation and removal of UV photoproducts in telomeres isolated from UV irradiated cultured human cells. Damage is detected by immunospot blotting of telomeres with highly specific antibodies against UV photoproducts. This method is adaptable for measuring other types of DNA damage at telomeres as well.
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Measuring UV Photoproduct Repair in Isolated Telomeres and Bulk Genomic DNA. · full record | OpenQuestion