Evidence map›Paper›PMID 31127490›Full record

ArticleDiabetes therapy : research, treatment and education of diabetes and related disorders2019

Post-Basal Insulin Intensification and Healthcare Resource Use in Type 2 Diabetes: A Web-Based Physician Survey in the United States and United Kingdom.

Meryl Brod, Amaury Basse, Marie Markert, Kathryn M Pfeiffer

Open access · goldAbstract read
In one paragraph

Article in Diabetes therapy : research, treatment and education of diabetes and related disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Meryl BrodThe Brod Group, 219 Julia Avenue, Mill Valley, CA, 94941, USA. mbrod@thebrodgroup.net.ORCID http://orcid.org/0000-0002-0663-5838
Amaury BasseNovo Nordisk A/S, Vandtaarnsvej 114, 2860, Soeborg, Denmark.
Marie MarkertNovo Nordisk A/S, Vandtaarnsvej 114, 2860, Soeborg, Denmark.
Kathryn M PfeifferThe Brod Group, 219 Julia Avenue, Mill Valley, CA, 94941, USA.
Brod Group · USNovo Nordisk (Denmark) · DK

Funding

Novo Nordisk A/S not applicable
6 · The paper itself

Abstract

introductionCurrently, there is limited knowledge of the healthcare resources and time needed to intensify patients with type 2 diabetes (T2D) treated with basal insulin to more complex treatment regimens. The purpose of the study was to investigate physicians' perspectives on the time and healthcare resources required for post-basal insulin intensification to basal-bolus and to basal in combination with a glucagon-like peptide-1 receptor agonist (GLP-1) regimens. The study also examined referrals to specialists for intensification and patient challenges with intensification.

methodsA web-based survey of physicians was conducted in the United Kingdom (UK) and the United States (USA).

resultsA total of 458 physicians completed the survey, including general practitioners (58.5%) and specialists (endocrinologists/diabetologists; 41.5%). On average, 7.0 healthcare provider (HCP) visits (SD 3.7) over 30.1 weeks (SD 17.4) were required to intensify to a basal-bolus regimen, while 5.7 HCP visits (SD 3.8) over 23.5 weeks (SD 15.2) were needed to intensify to basal insulin in combination with GLP-1. Referral to a specialist for intensification required on average an additional 8 weeks of wait time before intensification. Physicians reported that the complexity of the basal-bolus regimen and frequent injections were key challenges for T2D patients intensifying to basal-bolus, while frequent injections and side effects were key challenges for those intensifying with GLP-1.

conclusionLess complex regimens for intensification following basal insulin may help reduce the time and healthcare resources required for intensification and address some of the challenges T2D patients face when intensifying to basal-bolus or basal with GLP-1.

fundingNovo Nordisk, A/S.

Indexed as

Basal–bolus insulin therapyDiabetesDiabetes managementGLP-1 receptor agonistsHealthcare resource useInsulin intensification

Identifiers

PMID31127490
PMCPMC6612333
OpenAlexW2945207910

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.