Evidence map›Paper›PMID 31127476›Full record

ReviewJournal of assisted reproduction and genetics2019

Cryostorage failures: a medicolegal review.

Christopher P Moutos, Rana Lahham, John Y Phelps

2 registry-linked trialsAbstract readReview
In one paragraph

Review in Journal of assisted reproduction and genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05326802 completednot on this mapstarted 2022, after this paper: background citation

Occupational Physical and Mental Health Issues Experienced by U.S. Embryologists

TypeobservationalSponsorTMRW Life SciencesRan2022 to 2022Enrolled246ConditionsFatigue, Stress, Burnout, Professional, Musculoskeletal Pain
NCT05708963 completednot on this mapstarted 2023, after this paper: background citation

Occupational Physical Health Issues, Stress, Fatigue, and Burnout Experienced by U.K. Embryologists

TypeobservationalSponsorTMRW Life SciencesRan2023 to 2023Enrolled123ConditionsFatigue, Stress, Burnout, Professional, Musculoskeletal Pain
3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Liability for embryo mix-ups in fertility practices in the USA.Journal of assisted reproduction and genetics · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Christopher P MoutosDepartment of Obstetrics & Gynecology, The University of Texas Medical Branch at Galveston, 301 University Blvd, Galveston, TX, 77555, USA.
Rana LahhamSchool of Medicine, The University of Texas Medical Branch at Galveston, 301 University Blvd, Galveston, TX, 77555, USA.
John Y PhelpsDepartment of Obstetrics & Gynecology, The University of Texas Medical Branch at Galveston, 301 University Blvd, Galveston, TX, 77555, USA. jyphelps@aol.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo heighten awareness of the potential legal and financial burdens faced by those providing cryopreservation storage services of embryos and gametes in light of recent lawsuits involving inadvertent thawing of specimens.

methodsCase law review of US legal databases and courthouse dockets with a focus on lawsuits against reproductive endocrinologists and cryostorage facilities offering cryopreservation. Emphasis was placed on court decisions, awarded damages, and legal and media coverage related to cryostorage failure events.

resultsLawsuits pertaining to two notable ongoing cases of cryostorage failure that occurred at fertility clinics in the US in 2018 were reviewed. Media coverage of these events and plaintiff and defense attorney strategies were evaluated. Legal documents from previous, similar cryostorage failures were also reviewed. Common claims in cryostorage system failures include breach of contract and negligent handling of property. Facilities offering cryostorage services are vulnerable to significant burden, legally and financially, if they are to experience a storage system failure.

conclusionProviding cryostorage services is not without significant financial risk. Inadvertent thawing of specimens can lead to high damage awards against cryostorage facilities and those individuals linked to a cryostorage failure event. Because monetary damages can surpass insurance policy limits, those providing cryostorage services should be aware of plaintiff attorney strategies, common legal defenses, and basic asset protection principles to safeguard themselves if ever faced with these situations. Facilities should also carry out regular maintenance and safety checks on equipment and alarm structures to deter such events.

Indexed as

CryopreservationSpecimen HandlingFemaleGerm CellsHumansMaleMalpracticeReproductive Techniques, AssistedCryopreservationCryostorageEmbryoLiabilityMedical negligence

Identifiers

PMID31127476
PMCPMC6603075

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.