ArticleJournal of materials science. Materials in medicine2019
Efficacy of novel nano-hydroxyapatite/polyurethane composite scaffolds with silver phosphate particles in chronic osteomyelitis.
Article in Journal of materials science. Materials in medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Nanohydroxyapatite and its composite scaffold for bone tissue engineering application: a systematic review.Journal of materials science. Materials in medicine · 2025Pooled it
- Biomaterial-mediated macrophage polarization remodeling and sequential regulation: a potential strategy in bone infections treatment.Bone research · 2025Review
- Advancements in Wearable and Implantable BioMEMS Devices: Transforming Healthcare Through Technology.Micromachines · 2025Review
- Biomimetic Polyurethanes in Tissue Engineering.Biomimetics (Basel, Switzerland) · 2025Review
- Research progress of implantable materials in antibacterial treatment of bone infection.Frontiers in bioengineering and biotechnology · 2025Review
- Prospects and challenges for the application of tissue engineering technologies in the treatment of bone infections.Bone research · 2024Review
- Rapid and effective treatment of chronic osteomyelitis by conductive network-like MoSBioactive materials · 2024Article
- Injectable systems of chitosan in situ forming composite gel incorporating linezolid-loaded biodegradable nanoparticles for long-term treatment of bone infections.Drug delivery and translational research · 2024Article
- Establishment of a mandible defect model in rabbits infected with multiple bacteria and bioinformatics analysis.Frontiers in bioengineering and biotechnology · 2024Article
- Choosing the right animal model for osteomyelitis research: Considerations and challenges.Journal of orthopaedic translation · 2023Review
- Nanomaterial-assisted theranosis of bone diseases.Bioactive materials · 2023Review
- Evaluation of safety and efficacy of the bone marrow mesenchymal stem cell and gelatin-nano-hydroxyapatite combination in canine femoral defect repair.Frontiers in veterinary science · 2023Article
- Dual-functional composite scaffolds for inhibiting infection and promoting bone regeneration.Materials today. Bio · 2022Review
- Antimicrobial Biomaterials for the Healing of Infected Bone Tissue: A Systematic Review of Microtomographic Data on Experimental Animal Models.Journal of functional biomaterials · 2022Review
- Biodegradable Bone Implants as a New Hope to Reduce Device-Associated Infections-A Systematic Review.Bioengineering (Basel, Switzerland) · 2022Review
- Is Silver the New Gold? A Systematic Review of the Preclinical Evidence of Its Use in Bone Substitutes as Antiseptic.Antibiotics (Basel, Switzerland) · 2022Review
- Biological Effects, Applications and Design Strategies of Medical Polyurethanes Modified by Nanomaterials.International journal of nanomedicine · 2022Review
- Recent advances in the local antibiotics delivery systems for management of osteomyelitis.Drug delivery · 2021Review
- A Bone-Targeting Enoxacin Delivery System to Eradicate Staphylococcus Aureus-Related Implantation Infections and Bone Loss.Frontiers in bioengineering and biotechnology · 2021Article
- MRI Manifestations and Diagnostic Value of Chronic Osteomyelitis.Journal of healthcare engineering · 2021Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recently, chronic osteomyelitis is still a challenging surgical problem. Unfortunately, the traditional clinical method using bone cement loaded antibiotics is restricted due to its non-biodegradability and limited release of antibiotics. Hydroxyapatite is a good adsorbent with good biocompatibility, an ideal bone repair material, and can avert the requirement for the secondary surgical procedure of removal. In this study, nano-hydroxyapatite combined with a polyurethane containing 3% silver (Ag/n-HA/PU) was synthesized, and investigated for its efficacy of treating chronic bone infection with bone defects. To clarify its silver ions release characteristics, the concentration of the Ag
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.