ArticleScientific reports2019
High-resolution phase-contrast imaging of biological specimens using a stable betatron X-ray source in the multiple-exposure mode.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Ultra-high-brightness and tuneable attosecond-long electron beams with the laser wake field acceleration.Scientific reports · 2025Article
- Reconstruction of lateral coherence and 2D emittance in plasma betatron X-ray sources.Scientific reports · 2024Article
- Femtosecond multimodal imaging with a laser-driven X-ray source.Communications physics · 2023Article
- Acquisition of a single grid-based phase-contrast X-ray image using instantaneous frequency and noise filtering.Biomedical engineering online · 2022Article
- Non-destructive morphological observation of anatomical growth process in Haemaphysalis Longicornis tick specimens using optical coherence tomography.Technology and health care : official journal of the European Society for Engineering and Medicine · 2022Article
- Laser-driven x-ray and proton micro-source and application to simultaneous single-shot bi-modal radiographic imaging.Nature communications · 2020Article
- Exploring phase contrast imaging with a laser-based KScientific reports · 2020Article
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Authors and funding
11 authors.
Funding
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Abstract
Phase-contrast imaging using X-ray sources with high spatial coherence is an emerging tool in biology and material science. Much of this research is being done using large synchrotron facilities or relatively low-flux microfocus X-ray tubes. An alternative high-flux, ultra-short and high-spatial-coherence table-top X-ray source based on betatron motions of electrons in laser wakefield accelerators has the promise to produce high quality images. In previous phase-contrast imaging studies with betatron sources, single-exposure images with a spatial resolution of 6-70 μm were reported by using large-scale laser systems (60-200 TW). Furthermore, images obtained with multiple exposures tended to have a reduced contrast and resolution due to the shot-to-shot fluctuations. In this article, we demonstrate that a highly stable multiple-exposure betatron source, with an effective average source size of 5 μm, photon number and pointing jitters of <5% and spectral fluctuation of <10%, can be obtained by utilizing ionization injection in pure nitrogen plasma using a 30-40 TW laser. Using this source, high quality phase-contrast images of biological specimens with a 5-μm resolution are obtained for the first time. This work shows a way for the application of high resolution phase-contrast imaging with stable betatron sources using modest power, high repetition-rate lasers.
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