Evidence map›Paper›PMID 31127140›Full record

ArticleScientific reports2019

Y-chromosomal connection between Hungarians and geographically distant populations of the Ural Mountain region and West Siberia.

Helen Post, Endre Németh, László Klima, Rodrigo Flores, Tibor Fehér, Attila Türk, Gábor Székely, Hovhannes Sahakyan, Mayukh Mondal, Francesco Montinaro and 8 more

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Helen PostInstitute of Genomics, Estonian Biocentre, University of Tartu, Tartu, 51010, Estonia. helen2po@ut.ee.ORCID http://orcid.org/0000-0002-9112-7589
Endre NémethHungarian Natural History Museum, Department of Anthropology, Budapest, 1083, Hungary.
László KlimaEötvös Loránd University Budapest, Department of Finno-Ugric Studies, Budapest, 1088, Hungary.
Rodrigo FloresInstitute of Genomics, Estonian Biocentre, University of Tartu, Tartu, 51010, Estonia.
Tibor FehérHungarian Natural History Museum, Department of Anthropology, Budapest, 1083, Hungary.
Attila TürkPázmány Péter Catholic University, Faculty of Humanities and Social Sciences, Department of Early Hungarian and Migration Period Archaeology, Piliscsaba, 2087, Hungary.
Gábor SzékelyHungarian Natural History Museum, Department of Anthropology, Budapest, 1083, Hungary.
Hovhannes SahakyanInstitute of Genomics, Estonian Biocentre, University of Tartu, Tartu, 51010, Estonia.ORCID http://orcid.org/0000-0003-1596-2838
Mayukh MondalInstitute of Genomics, Estonian Biocentre, University of Tartu, Tartu, 51010, Estonia.ORCID http://orcid.org/0000-0003-0122-0323
Francesco MontinaroInstitute of Genomics, Estonian Biocentre, University of Tartu, Tartu, 51010, Estonia.
Monika KarminInstitute of Genomics, Estonian Biocentre, University of Tartu, Tartu, 51010, Estonia.ORCID http://orcid.org/0000-0001-9827-5579
Lauri SaagInstitute of Genomics, Estonian Biocentre, University of Tartu, Tartu, 51010, Estonia.
Bayazit YunusbayevInstitute of Genomics, Estonian Biocentre, University of Tartu, Tartu, 51010, Estonia.ORCID http://orcid.org/0000-0002-6035-8763
Elza K KhusnutdinovaInstitute of Biochemistry and Genetics, Ufa Scientific Center of RAS, Ufa, 450054, Russia.ORCID http://orcid.org/0000-0003-2987-3334
Ene MetspaluInstitute of Genomics, Estonian Biocentre, University of Tartu, Tartu, 51010, Estonia.
Richard VillemsInstitute of Genomics, Estonian Biocentre, University of Tartu, Tartu, 51010, Estonia.
Kristiina TambetsInstitute of Genomics, Estonian Biocentre, University of Tartu, Tartu, 51010, Estonia.ORCID http://orcid.org/0000-0002-8173-6380
Siiri RootsiInstitute of Genomics, Estonian Biocentre, University of Tartu, Tartu, 51010, Estonia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hungarians who live in Central Europe today are one of the westernmost Uralic speakers. Despite of the proposed Volga-Ural/West Siberian roots of the Hungarian language, the present-day Hungarian gene pool is highly similar to that of the surrounding Indo-European speaking populations. However, a limited portion of specific Y-chromosomal lineages from haplogroup N, sometimes associated with the spread of Uralic languages, link modern Hungarians with populations living close to the Ural Mountain range on the border of Europe and Asia. Here we investigate the paternal genetic connection between these spatially separated populations. We reconstruct the phylogeny of N3a4-Z1936 clade by using 33 high-coverage Y-chromosomal sequences and estimate the coalescent times of its sub-clades. We genotype close to 5000 samples from 46 Eurasian populations to show the presence of N3a4-B539 lineages among Hungarians and in the populations from Ural Mountain region, including Ob-Ugric-speakers from West Siberia who are geographically distant but linguistically closest to Hungarians. This sub-clade splits from its sister-branch N3a4-B535, frequent today among Northeast European Uralic speakers, 4000-5000 ya, which is in the time-frame of the proposed divergence of Ugric languages.

Indexed as

Chromosomes, Human, YGene PoolGenetics, PopulationHaplotypesHumansHungaryLanguagePhylogenyPhylogeographySiberiaWhite People

Identifiers

PMID31127140
PMCPMC6534673

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.