ArticleNature communications2019
Proton mediated spin state transition of cobalt heme analogs.
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed.
- Electronic Modulation of NiO by Cu Doping Toward Enhanced Electrocatalytic Ethylene Glycol Oxidation to Formate.ChemSusChem · 2026Article
- Spin chemistry: the key to revolutionizing energy storage and conversion efficiency.Chemical science · 2025Review
- Proton-Induced Switching of Paramagnetism: Reversible Conversion between a Low and High Spin CoJournal of the American Chemical Society · 2025Article
- Modulating the oxygen affinity of porphyrins with metals, ligands, and functional groups: A DFT study.Journal of computational chemistry · 2025Article
- Stereochemistry of low-spin cobalt porphyrins. 9. Molecular stereochemistry of two picket fence cobalt(II) derivatives.Journal of inorganic biochemistry · 2023Article
- 2D Zn-Porphyrin-Based Co(II)-MOF with 2-Methylimidazole Sitting Axially on the Paddle-Wheel Units: An Efficient Electrochemiluminescence Bioassay for SARS-CoV-2.Advanced functional materials · 2022Article
- Ru(II)Porphyrinate-based molecular nanoreactor for carbene insertion reactions and quantitative formation of rotaxanes by active-metal-template syntheses.Nature communications · 2020Article
Corrections and comments
- Erratum issued
Authors and funding
12 authors.
Funding
Abstract
The spin state transition from low spin to high spin upon substrate addition is one of the key steps in cytochrome P450 catalysis. External perturbations such as pH and hydrogen bonding can also trigger the spin state transition of hemes through deprotonated histidine (e.g. Cytochrome c). In this work, we report the isolated 2-methylimidazole Cobalt(II) [Co(TPP)(2-MeHIm)] and [Co(TTP)(2-MeHIm)], and the corresponding 2-methylimidazolate derivatives where the N-H proton of axial 2-MeHIm is removed. Interestingly, various spectroscopies including EPR and XAFS determine a high-spin state (S = 3/2) for the imidazolate derivatives, in contrast to the low-spin state (S = 1/2) of all known imidazole analogs. DFT assisted stereoelectronic investigations are applied to understand the metal-ligand interactions, which suggest that the dramatically displaced metal center allowing a promotion e
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