Evidence map›Paper›PMID 31127000›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2019

Luyu Liu, Yevgen Yudin, Janhavi Nagwekar, Chifei Kang, Natalia Shirokova, Tibor Rohacs

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.7field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Deep mutational scan of the pore of the cold-sensing TRPM8 channel.bioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Review
  5. Navigating the Controversies: Role of TRPM Channels in Pain States.International journal of molecular sciences · 2024
    Review
  6. Article
  7. Article
  8. Review
  9. Nitric oxide resets kisspeptin-excited GnRH neurons via PIP2 replenishment.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  10. Article
  11. Review
  12. The cool things to know about TRPM8!Channels (Austin, Tex.) · 2020
    Review
  13. Review
  14. Article
  15. Diacylglycerol kinases regulate TRPV1 channel activity.The Journal of biological chemistry · 2020
    Article
  16. Article
  17. Article
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Luyu LiuDepartment of Pharmacology, Physiology and Neuroscience, Rutgers New Jersey Medical School, Newark, New Jersey 07103.
Yevgen YudinDepartment of Pharmacology, Physiology and Neuroscience, Rutgers New Jersey Medical School, Newark, New Jersey 07103.ORCID 0000-0002-0663-6435
Janhavi NagwekarDepartment of Pharmacology, Physiology and Neuroscience, Rutgers New Jersey Medical School, Newark, New Jersey 07103.
Chifei KangDepartment of Pharmacology, Physiology and Neuroscience, Rutgers New Jersey Medical School, Newark, New Jersey 07103.
Natalia ShirokovaDepartment of Pharmacology, Physiology and Neuroscience, Rutgers New Jersey Medical School, Newark, New Jersey 07103.
Tibor RohacsDepartment of Pharmacology, Physiology and Neuroscience, Rutgers New Jersey Medical School, Newark, New Jersey 07103 tibor.Rohacs@rutgers.edu.ORCID 0000-0003-3580-2575
Rutgers, The State University of New Jersey · US

Funding

Regulation of sensory TRP channels by phospholipids and G-proteinsR01NS055159 · NINDS · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI ROHACS, TIBOR · 2007 to 2022
$5.9M
Regulation of the Intestinal Ca2+ Channels TRPV6R01GM093290 · NIGMS · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI CARNEVALE, VINCENZO, ROHACS, TIBOR · 2011 to 2025
$4.9M
Molecular mechanism of TRPV1 activationR01GM131048 · NIGMS · TEMPLE UNIV OF THE COMMONWEALTH · PI CARNEVALE, VINCENZO, ROHACS, TIBOR · 2019 to 2022
$1.4M
NIGMS NIH HHS R01 GM093290NIGMS NIH HHS R01 GM131048NINDS NIH HHS R01 NS055159
6 · The paper itself

Abstract

The cold- and menthol-sensitive transient receptor potential melastatin 8 (TRPM8) channel is important for both physiological temperature detection and cold allodynia. Activation of G-protein-coupled receptors (GPCRs) by proinflammatory mediators inhibits these channels. It was proposed that this inhibition proceeds via direct binding of

Indexed as

AnimalsFemaleGanglia, SpinalGTP-Binding Protein alpha SubunitsInflammationMaleMiceMice, Inbred C57BLPhosphatidylinositol 4,5-DiphosphateTRPM Cation ChannelsGTP-Binding Protein alpha SubunitsPhosphatidylinositol 4,5-DiphosphateTRPM8 protein, mouseTRPM Cation ChannelsDRG neuronGPCRG-proteinPIP2TRPM8

Identifiers

PMID31127000
PMCPMC6668199
OpenAlexW2949718514

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.