ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2019
The Large-Scale Organization of Gestures and Words in the Middle Temporal Gyrus.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
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Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.
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- The Comodification of Brain Activity, Functional Connectivity, and Behavior Following Learning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Investigating action topography in visual cortex and deep artificial neural networks.Nature communications · 2025Article
- Conservation of glial density and cell-type ratios within a brain region across mammals.PNAS nexus · 2025Article
- Revealing Key Dimensions Underlying the Recognition of Dynamic Human Actions.Communications psychology · 2025Article
- Neural Plasticity Induced by Working Memory Training: Insights From Cortical Microstructure and Transcriptional Profiles.CNS neuroscience & therapeutics · 2025Article
- Unravelling the genetic and molecular basis of low-frequency rTMS induced changes in functional connectivity density in schizophrenia patients with auditory verbal hallucinations.Translational psychiatry · 2025Article
- Layer-Specific Colocalization of Microglia with Amyloid Plaques in the Middle Temporal Gyrus Predicts Cognitive Decline in Alzheimer's Disease.Aging and disease · 2025Article
- Cognitive neuropsychological and neuroanatomic predictors of naturalistic action performance in left hemisphere stroke: A retrospective analysis.Cortex; a journal devoted to the study of the nervous system and behavior · 2025Article
- Cognitive neuropsychological and neuroanatomic predictors of naturalistic action performance in left hemisphere stroke: a retrospective analysis.bioRxiv : the preprint server for biology · 2025Article
- Differential Abnormality in Regional Brain Spontaneous Activity and Functional Connectivity in Patients of Non-Acute Subcortical Stroke With Versus Without Global Cognitive Functional Impairment.Brain and behavior · 2025Article
- The spatiotemporal neural dynamics of action-related features underlying action recognition.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Beyond the left cerebral hemisphere: bilateral language lateralization in healthy aging and its clinical implications.Frontiers in aging neuroscience · 2025Article
- Dynamic Field Theory of Executive Function: Identifying Early Neurocognitive Markers.Monographs of the Society for Research in Child Development · 2024Article
- Integrated multimodal cell atlas of Alzheimer's disease.Nature neuroscience · 2024Article
- SEA-AD is a multimodal cellular atlas and resource for Alzheimer's disease.Nature aging · 2024Article
- Article
- Sensitivity and specificity of the action observation network to kinematics, target object, and gesture meaning.Human brain mapping · 2024Article
- The angular gyrus serves as an interface between the non-lexical reading network and the semantic system: evidence from dynamic causal modeling.Brain structure & function · 2024Article
- Altered spontaneous brain activity patterns in hypertensive retinopathy using fractional amplitude of low-frequency fluctuations: a functional magnetic resonance imaging study.International journal of ophthalmology · 2024Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The middle temporal gyrus (MTG) has been shown to be recruited during the processing of words, but also during the observation of actions. Here we investigated how information related to words and gestures is organized along the MTG. To this aim, we measured the BOLD response in the MTG to video clips of gestures and spoken words in 17 healthy human adults (male and female). Gestures consisted of videos of an actress performing object-use pantomimes (iconic representations of object-directed actions; e.g., playing guitar), emblems (conventional gestures, e.g., thumb up), and meaningless gestures. Word stimuli (verbs, nouns) consisted of video clips of the same actress pronouncing words. We found a stronger response to meaningful compared with meaningless gestures along the whole left and large portions of the right MTG. Importantly, we observed a gradient, with posterior regions responding more strongly to gestures (pantomimes and emblems) than words and anterior regions showing a stronger response to words than gestures. In an intermediate region in the left hemisphere, the response was significantly higher to words and emblems (i.e., items with a greater arbitrariness of the sign-to-meaning mapping) than to pantomimes. These results show that the large-scale organization of information in the MTG is driven by the input modality and may also reflect the arbitrariness of the relationship between sign and meaning.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.