Evidence map›Paper›PMID 31126994›Full record

ArticleLife science alliance2019

The hypoxia-response pathway modulates RAS/MAPK-mediated cell fate decisions in

Sabrina Maxeiner, Judith Grolleman, Tobias Schmid, Jan Kammenga, Alex Hajnal

Open access · goldAbstract read
In one paragraph

Article in Life science alliance, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

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  9. Innate immunity in C. elegans.Current topics in developmental biology · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Sabrina MaxeinerInstitute of Molecular Life Sciences, University of Zurich, Zurich, Switzerland.
Judith GrollemanLaboratory of Nematology, Wageningen University, Wageningen, The Netherlands.
Tobias SchmidInstitute of Molecular Life Sciences, University of Zurich, Zurich, Switzerland.
Jan KammengaLaboratory of Nematology, Wageningen University, Wageningen, The Netherlands.ORCID 0000-0003-4822-4436
Alex HajnalInstitute of Molecular Life Sciences, University of Zurich, Zurich, Switzerland alex.hajnal@imls.uzh.ch.ORCID 0000-0002-4098-3721
University of Zurich · CHWageningen University & Research · NL

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
NIH HHS P40 OD010440
6 · The paper itself

Abstract

Animals need to adjust many cellular functions to oxygen availability to adapt to changing environmental conditions. We have used the nematode

Indexed as

Signal TransductionAlternative SplicingAnimalsBiomarkersCaenorhabditis elegansCaenorhabditis elegans ProteinsGain of Function MutationGene Expression RegulationHypoxiaMitogen-Activated Protein KinasesModels, BiologicalPhenotypeProtein BindingProto-Oncogene Proteins p21(ras)Receptors, NotchTranscription FactorsBiomarkersCaenorhabditis elegans ProteinsHIF-1 protein, C elegansMitogen-Activated Protein KinasesProto-Oncogene Proteins p21(ras)Receptors, NotchTranscription Factors

Identifiers

PMID31126994
PMCPMC6536719
OpenAlexW2946252488

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.