ArticleThe Journal of experimental medicine2019
Immune homeostasis and regulation of the interferon pathway require myeloid-derived Regnase-3.
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Article in The Journal of experimental medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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0cells of the map it votes in
25citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
What it found
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Who cites it
25 citing papers in PubMed, 41 citations in OpenAlex.
- Article
- Blimp-1 integrates alarmin signals in ILC2s and drives proinflammatory functions required for type 2 immunity.The Journal of experimental medicine · 2026Article
- Lipoteichoic Acid Stimulation of Macrophages Causes Mitochondrial Dysfunction.International dental journal · 2026Article
- The Regnase pathway: a core axis in immune regulation and inflammatory disease.Frontiers in immunology · 2026Review
- Macrophage Zc3h12c Limits Tissue Inflammation and Injury via Alternative Splicing of Pre-mRNA.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- MCPIP3/Regnase-3 binds 14-3-3 proteins and contributes to the regulation of the cell cycle in human immortalized keratinocytes.Scientific reports · 2025Article
- MCPIP3 orchestrates the balance of epidermal proliferation and differentiation.Cell communication and signaling : CCS · 2025Article
- Identification of locally advanced rectal cancer-related genes based on transcriptome and mendelian randomization analysis with biological validation.Frontiers in immunology · 2025Article
- Crosstalk between Regnase-1 and -3 shapes mast cell survival and cytokine expression.Life science alliance · 2024Article
- Regulation of inflammatory diseases via the control of mRNA decay.Inflammation and regeneration · 2024Review
- ZFP36 disruption is insufficient to enhance the function of mesothelin-targeting human CAR-T cells.Scientific reports · 2024Article
- Regulation of tumor metastasis and CD8Cellular & molecular biology letters · 2024Article
- The homeostatic function of Regnase-2 restricts neuroinflammation.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2023Article
- Article
- ZC3H12C expression in dendritic cells is necessary to prevent lymphadenopathy of skin-draining lymph nodes.Immunology and cell biology · 2022Article
- Pan-Cancer Analysis Predicts the Immunological and Prognostic Role of ZC3H12C in KIRC.BioMed research international · 2022Article
- RNA-binding proteins and RNA methylation in myeloid cells.Immunological reviews · 2021Review
- Molecular Mechanisms of ZC3H12C/Reg-3 Biological Activity and Its Involvement in Psoriasis Pathology.International journal of molecular sciences · 2021Article
- The RNase MCPIP3 promotes skin inflammation by orchestrating myeloid cytokine response.Nature communications · 2021Article
- PIN and CCCH Zn-finger domains coordinate RNA targeting in ZC3H12 family endoribonucleases.Nucleic acids research · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
26 authors at 8 institutions in 1 country.
Matthias von GammInstitute for Diabetes and Obesity, Helmholtz Diabetes Center at Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
Annalisa Schaub *Institute for Diabetes and Obesity, Helmholtz Diabetes Center at Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.ORCID 0000-0002-0408-5297
Alisha N Jones *Institute of Structural Biology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
Christine WolfInstitute of Environmental Medicine, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
Gesine BehrensInstitute for Immunology, Biomedical Center, Ludwig-Maximilians-Universität München, Planegg-Martinsried, Germany.
Johannes LichtiInstitute for Diabetes and Obesity, Helmholtz Diabetes Center at Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
Katharina EssigRoche Pharma Research and Early Development, Large Molecule Research, Roche Innovation Center Munich, Penzberg, Germany.
Anna MachtInstitute for Diabetes and Obesity, Helmholtz Diabetes Center at Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
Joachim PircherMedizinische Klinik und Poliklinik I, Klinikum der Universität München, Ludwig-Maximilians-University, Munich, Germany.
Andreas EhrlichMedizinische Klinik und Poliklinik I, Klinikum der Universität München, Ludwig-Maximilians-University, Munich, Germany.ORCID 0000-0001-5944-7323
Kathrin DavariMedigene Immunotherapies, Planegg-Martinsried, Germany.
Dhruv ChauhanGene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany.
Benjamin BuschMax von Pettenkofer-Institut für Hygiene und Medizinische Mikrobiologie, Ludwig-Maximilians-Universität München, Munich, Germany.ORCID 0000-0003-0519-9816
Wolfgang WurstInstitute of Developmental Genetics, Helmholtz Zentrum München, Munich, Germany.
Regina FeederleMonoclonal Antibody Core Facility, Institute for Diabetes and Obesity, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.ORCID 0000-0002-3981-367X
Annette FeuchtingerResearch Unit Analytical Pathology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
Matthias H TschöpInstitute for Diabetes and Obesity, Helmholtz Diabetes Center at Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
Caroline C FriedelInstitute for Informatics, Ludwig-Maximilians-Universität München, Munich, Germany.
Stefanie M HauckResearch Unit Protein Science, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.ORCID 0000-0002-1630-6827
Michael SattlerInstitute of Structural Biology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.ORCID 0000-0002-1594-0527
Arie GeerlofInstitute of Structural Biology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.ORCID 0000-0001-7295-9948
Veit HornungGene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany.
Vigo HeissmeyerInstitute for Immunology, Biomedical Center, Ludwig-Maximilians-Universität München, Planegg-Martinsried, Germany.
Christian Schulz *Medizinische Klinik und Poliklinik I, Klinikum der Universität München, Ludwig-Maximilians-University, Munich, Germany.
Mathias Heikenwalder *Division of Chronic Inflammation and Cancer (F180), German Cancer Research Center, Heidelberg, Germany.
Elke GlasmacherInstitute for Diabetes and Obesity, Helmholtz Diabetes Center at Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany Elke.glasmacher@gmail.com.ORCID 0000-0003-1265-2543
Helmholtz Zentrum München · DELudwig-Maximilians-Universität München · DELMU Klinikum · DECenter for Integrated Protein Science Munich · DEGerman Cancer Research Center · DEGerman Center for Neurodegenerative Diseases · DEMedigene (Germany) · DERoche Pharma AG (Germany) · DE
Funding
No grant is acknowledged in the PubMed record.
Abstract
The RNase Regnase-1 is a master RNA regulator in macrophages and T cells that degrades cellular and viral RNA upon NF-κB signaling. The roles of its family members, however, remain largely unknown. Here, we analyzed
Indexed as
Immunity, Innate3' Untranslated RegionsAnimalsAutoimmunityB-LymphocytesFlow CytometryGene Expression RegulationHomeostasisInterferonsMacrophagesMiceMice, Inbred C57BLMice, KnockoutMyeloid CellsReal-Time Polymerase Chain ReactionRibonucleases3' Untranslated RegionsInterferonsRibonucleasesZc3h12c protein, mouse
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.