Evidence map›Paper›PMID 31126950›Full record

ArticleApplied and environmental microbiology2019

β-Aminopeptidases: Insight into Enzymes without a Known Natural Substrate.

Marietta John-White, James Gardiner, Priscilla Johanesen, Dena Lyras, Geoffrey Dumsday

Open access · bronzeAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Frontiers in bioengineering and biotechnology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Marietta John-WhiteCSIRO Manufacturing, Clayton, Victoria, Australia.
James GardinerCSIRO Manufacturing, Clayton, Victoria, Australia.
Priscilla JohanesenInfection and Immunity Program, Monash Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia.
Dena LyrasInfection and Immunity Program, Monash Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia.ORCID 0000-0003-2345-9271
Geoffrey DumsdayCSIRO Manufacturing, Clayton, Victoria, Australia Geoff.Dumsday@csiro.au.ORCID 0000-0002-5080-8791
Australian Regenerative Medicine Institute · AUCSIRO Manufacturing · AU

Funding

Translational Research Center to Expedite Novel Therapies in Cystic FibrosisP30DK089507 · NIDDK · SEATTLE CHILDREN'S HOSPITAL · PI Christopher Hooper Goss · 2010 to 2026
$21.4M
NIDDK NIH HHS P30 DK089507
6 · The paper itself

Abstract

β-Aminopeptidases have the unique capability to hydrolyze N-terminal β-amino acids, with varied preferences for the nature of β-amino acid side chains. This unique capability makes them useful as biocatalysts for synthesis of β-peptides and to kinetically resolve β-peptides and amides for the production of enantiopure β-amino acids. To date, six β-aminopeptidases have been discovered and functionally characterized, five from Gram-negative bacteria and one from a fungus,

Indexed as

AminopeptidasesBacterial ProteinsBurkholderiaFungal ProteinsKineticsMycobacteriaceaeSubstrate SpecificityYarrowiaAminopeptidasesBacterial ProteinsFungal Proteinsenzymesβ-amino acidsβ-aminopeptidasesβ-peptides

Identifiers

PMID31126950
PMCPMC6643246
OpenAlexW2945089876

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.