Evidence map›Paper›PMID 31126754›Full record

ReviewTrends in endocrinology and metabolism: TEM2019

Promises of Nanotherapeutics in Obesity.

Garrett I Ash, Dongin Kim, Mahua Choudhury

Abstract readReview
In one paragraph

Review in Trends in endocrinology and metabolism: TEM, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Targeted Nano-Based Systems for the Anti-Obesity Agent's Delivery.Advances in experimental medicine and biology · 2024
    Review
  8. Review
  9. 360-Degree Perspectives on Obesity.Medicina (Kaunas, Lithuania) · 2023
    Review
  10. Extracellular Vesicles and Obesity.Advances in experimental medicine and biology · 2023
    Review
  11. Review
  12. Review
  13. Article
  14. Review
  15. Polymeric Carriers for Controlled Drug Delivery in Obesity Treatment.Trends in endocrinology and metabolism: TEM · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Garrett I AshSchool of Nursing, Yale University, West Haven, CT, USA.
Dongin KimDepartment of Pharmaceutical Sciences, Irma Lerma Rangel College of Pharmacy, Texas A&M Health Science Center, College Station, TX, USA.
Mahua ChoudhuryDepartment of Pharmaceutical Sciences, Irma Lerma Rangel College of Pharmacy, Texas A&M Health Science Center, College Station, TX, USA. Electronic address: mchoudhury@pharmacy.tamhsc.edu.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Multidisciplinary Behavioral Research Training in T1DT32DK097718 · NIDDK · YALE UNIVERSITY · PI GREY, MARGARET, WEINZIMER, STUART ALAN · 2012 to 2017
$771k
Medical Research CouncilNCATS NIH HHS UL1 TR001863NIDDK NIH HHS T32 DK097718
6 · The paper itself

Abstract

The application of nanotechnology to medicine promises a wide range of new tools and possibilities, from earlier diagnostics and improved imaging, to better, more efficient, and more targeted therapies. This emerging field could help address obesity, with advances in drug delivery, nutraceuticals, and genetic and epigenetic therapeutics. Its application to obesity is still largely in the development phase. Here, we review the novel angle of nanotech applied to human consumable products and their specific applications to addressing obesity through nutraceuticals, with respect to benefits and limitations of current nanotechnology methods. Further, we review potential future applications to deliver genetic and epigenetic miRNA therapeutics. Finally, we discuss future directions, including theranostics, combinatory therapy, and personalized medicine.

Indexed as

Drug Delivery SystemsEpigenomicsHumansMicroRNAsNanoparticlesNanotechnologyObesityPrecision MedicineMicroRNAsdiabetesepigeneticsgene therapymiRNAnanotechnologyobesity

Identifiers

PMID31126754
PMCPMC6716370

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.