Evidence map›Paper›PMID 31126302›Full record

ArticleJournal of orthopaedic surgery and research2019

Efficacy of magnetic resonance imaging with an SPGR sequence for the early evaluation of knee cartilage degeneration and the relationship between cartilage and other tissues.

Xin Yang, Zhuoyang Li, Yongping Cao, Yufeng Xu, He Wang, Licheng Wen, Zhichao Meng, Heng Liu, Rui Wang, Xiang Li

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In one paragraph

Article in Journal of orthopaedic surgery and research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xin YangDepartment of Orthopedics, Peking University First Hospital, No. 8, Xishiku Street, Beijing, 100034, Beijing, China.
Zhuoyang LiDepartment of Orthopedics, Zhejiang University School of Medicine First Affiliated Hospital, No. 79, Qingchun Road, Hangzhou, 310000, Zhejiang, China.
Yongping CaoDepartment of Orthopedics, Peking University First Hospital, No. 8, Xishiku Street, Beijing, 100034, Beijing, China. freehorse6666@163.com.
Yufeng XuDepartment of Radiology, Peking University First Hospital, No. 8, Xishiku Street, Beijing, 100034, Beijing, China.
He WangDepartment of Radiology, Peking University First Hospital, No. 8, Xishiku Street, Beijing, 100034, Beijing, China.
Licheng WenDepartment of Orthopedics, Peking University First Hospital, No. 8, Xishiku Street, Beijing, 100034, Beijing, China.
Zhichao MengDepartment of Orthopedics, Peking University First Hospital, No. 8, Xishiku Street, Beijing, 100034, Beijing, China.
Heng LiuDepartment of Orthopedics, Peking University First Hospital, No. 8, Xishiku Street, Beijing, 100034, Beijing, China.
Rui WangDepartment of Orthopedics, Peking University First Hospital, No. 8, Xishiku Street, Beijing, 100034, Beijing, China.
Xiang LiDepartment of Orthopedics, Peking University First Hospital, No. 8, Xishiku Street, Beijing, 100034, Beijing, China.

Funding

Postdoctoral Research Foundation of China 2018M642459
6 · The paper itself

Abstract

RATIONALE AND

objectivesThe aim of this study was to investigate the efficacy of magnetic resonance imaging (MRI) with a spoiled gradient-recalled (SPGR) sequence to evaluate early knee cartilage degeneration and the relationship between cartilage and other tissues using a modified Whole-Organ Magnetic Resonance Imaging Score (WORMS). MATERIALS AND

methodsEighty-four patients with knee joint pain were evaluated by X-ray and MRI with an SPGR sequence from June 2015 to December 2016. Joint degeneration was graded by two experienced radiologists using the Kellgren-Lawrence (K-L) grading scale. The modified WORMS was used to evaluate cartilage lesions, bone marrow abnormalities, bone cysts, osteophytes, joint effusion and synovitis. The difference between the WORMS of the SPGR and the T2 sequences evaluated by the Wilcoxon signed-rank test was determined, and the relationships between the WORMS features were evaluated by a Spearman correlation.

resultsThe modified WORMS for the cartilage lesion evaluation was significantly higher with the SPGR sequence than with the T2 sequence (P < 0.05). The cartilage lesions showed a moderate correlation with osteophytes, synovitis and joint effusion (Rs > 0.40, P < 0.05) and weak correlations with bone marrow abnormalities and bone cysts (Rs < 0.4, P < 0.05).

conclusionThe modified WORMS evaluation using MRI with the SPGR sequence was much better than the normal sequence for early knee osteoarthritis (OA). The cartilage lesions are associated with bone marrow abnormalities and the other features of OA.

Indexed as

AdolescentAdultAgedArthralgiaCartilage, ArticularEarly DiagnosisFemaleHumansKnee JointMagnetic Resonance ImagingMaleMiddle AgedTreatment OutcomeYoung AdultCartilage lesionsMagnetic resonance imagingOsteoarthritisSpoiled gradient-recalled sequence

Identifiers

PMID31126302
PMCPMC6534879

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.