Evidence map›Paper›PMID 31126280›Full record

ArticleBMC ophthalmology2019

Functional and morphological results of treatment of macula-on and macula-off rhegmatogenous retinal detachment with pars plana vitrectomy and sulfur hexafluoride gas tamponade.

Dorota Borowicz, Katarzyna Nowomiejska, Dominika Nowakowska, Agnieszka Brzozowska, Mario D Toro, Teresio Avitabile, Anselm G Jünemann, Robert Rejdak

2 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in BMC ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03902795 completednot on this map

Functional and Morphological Results of macula-on and Macula-off Rhegmatogenous Retinal Detachment Treated With Pars Plana Vitrectomy and Sulfur Hexafluoride Gas Tamponade

TypeobservationalSponsorMedical University of LublinRan2016 to 2017Enrolled62ConditionsRetinal Detachment, VitrectomyArmsMicroperimetry, M-charts
NCT05538156 nanot yet recruitingnot on this mapstarted 2022, after this paper: background citation

Internal Limiting Membrane Peeling in Macula-off Retinal Detachment With Grade B Proliferative Vitreoretinopathy

TypeinterventionalSponsorCentral Hospital, Nancy, FranceRan2022 to 2027Enrolled126ConditionsRetinal Detachment, Proliferative VitreoretinopathyArmsControl group, Intervention group
3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 46 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Dorota BorowiczDepartment of General Ophthalmology, Medical University of Lublin, Poland, ul. Chmielna 1, 20-079, Lublin, Poland.
Katarzyna NowomiejskaDepartment of General Ophthalmology, Medical University of Lublin, Poland, ul. Chmielna 1, 20-079, Lublin, Poland. katarzynanowomiejska@mailcity.com.
Dominika NowakowskaDepartment of General Ophthalmology, Medical University of Lublin, Poland, ul. Chmielna 1, 20-079, Lublin, Poland.
Agnieszka BrzozowskaDepartment of Mathematics and Medical Biostatistics, Medical University, Lublin, Poland.
Mario D ToroDepartment of General Ophthalmology, Medical University of Lublin, Poland, ul. Chmielna 1, 20-079, Lublin, Poland.
Teresio AvitabileDepartment of Ophthalmology, University of Catania, Catania, Italy.
Anselm G JünemannDepartment of General Ophthalmology, Medical University of Lublin, Poland, ul. Chmielna 1, 20-079, Lublin, Poland.
Robert RejdakDepartment of General Ophthalmology, Medical University of Lublin, Poland, ul. Chmielna 1, 20-079, Lublin, Poland.
Medical University of Lublin · PLPolish Academy of Sciences · PLUniversity of Catania · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo examine morphological and functional results after pars plana vitrectomy (PPV) with sulfur hexafluoride (SF6) gas tamponade due to macula-on and macula-off rhegmatogenous retinal detachment (RRD) during 6 months of the follow-up.

methodsThe study included 62 eyes that underwent successful PPV with SF6 tamponade with macula-on (34 eyes) and macula-off (28 eyes) RRD preoperatively. The best-corrected visual acuity (BCVA), Amsler test, M-charts, optical coherence tomography (OCT) and microperimetry were performed at 1, 3 and 6 months postoperatively.

resultsResults of the Amsler test were abnormal postoperatively in 54% of the patients in the group with macula-off and in 32% of the patients with macula-on RRD. Horizontal M-charts improved significantly from 0.33 to 0.2, vertical M-charts- from 0.29 to 0.17 during 6 months of the follow-up. There was a significant increase in the central retinal thickness (CRT) and average thickness (AT) between follow-up examinations only in the macula-off group. 29 of 62 eyes (47%) after surgery (equally with macula-on and macula-off RRD) showed morphological changes in OCT in the macular region, as epiretinal membrane, macular edema, subretinal fluid or alterations of the outer layers of the retina. The average threshold in microperimetry increased significantly within both groups during the follow-up.

conclusionBoth horizontal and vertical M-charts scores, as were as microperimetry sensitivity improved significantly during the 6 months of the follow-up both in macula-on and macula-off group. Although PPV with SF6 gas tamponade was successful, almost half of eyes revealed anatomical changes in the macular region in OCT both with macula-on and macula-off group.

trial registrationCurrent Controlled Trials NCT03902795 registered on 03/04/2019. Retrospectively registered.

Indexed as

AdultAgedEndotamponadeFemaleHumansMacula LuteaMaleMiddle AgedRetinal DetachmentRetrospective StudiesSulfur HexafluorideTomography, Optical CoherenceVision DisordersVisual AcuityVitrectomySulfur HexafluorideM-chartsMetamorphopsiaMicroperimetryRhegmatogenous retinal detachment

Identifiers

PMID31126280
PMCPMC6534838
OpenAlexW2947035003

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.