SynthesisBMC geriatrics2019
Effects of the frailty phenotype on post-operative complications in older surgical patients: a systematic review and meta-analysis.
Synthesis in BMC geriatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Association of Preoperative High-Intensity Interval Training With Cardiorespiratory Fitness and Postoperative Outcomes Among Adults Undergoing Major Surgery: A Systematic Review and Meta-Analysis.JAMA network open · 2023Pooled it
- Association between mortality and frailty in emergency general surgery: a systematic review and meta-analysis.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022Pooled it
- The Impact of Frailty on Adverse Outcomes in Geriatric Hip Fracture Patients: A Systematic Review and Meta-Analysis.Frontiers in public health · 2022Pooled it
- Frailty and risk of complications in head and neck oncologic surgery. Systematic review and dose-response meta-analysis.Medicina oral, patologia oral y cirugia bucal · 2021Pooled it
- The Association of an Electronic Frailty Index with Glaucoma Shunt Outcomes.Geriatrics (Basel, Switzerland) · 2026Article
- Contemporary preoperative assessment for colorectal surgery: new insights and developments.BMJ open gastroenterology · 2026Review
- Integration of MSK-FI and clinical variables to predict postoperative complications after esophagectomy.Journal of thoracic disease · 2026Article
- Brazilian Portuguese Adaptation of the Updated Clinical Frailty Scale: Cross-Cultural Adaptation, Reliability, and Convergent Validity in Hospitalized Older Adults.Journal of aging research · 2026Article
- Huperzine A associated with improved early postoperative cognitive function after neurosurgery under general anesthesia: a randomized clinical trial.International journal of surgery (London, England) · 2025Article
- Postoperative outcomes following prehabilitationWorld journal of gastrointestinal surgery · 2025Article
- Performance of the early warning system score in predicting postoperative complications in older versus younger patients.Perioperative medicine (London, England) · 2025Article
- Frailty as Predictor for Early Functional Outcomes After Radical Prostatectomy.Journal of frailty, sarcopenia and falls · 2025Article
- Perioperative assessment and management of frailty in elderly patients: a national survey of Italian anesthesiologists.Journal of anesthesia, analgesia and critical care · 2025Article
- Using Existing Clinical Data to Measure Older Adult Inpatients' Frailty at Admission and Discharge: Hospital Patient Register Study.JMIR aging · 2024Article
- Postoperative neurocognitive disorders in ambulatory surgery: a narrative review.Korean journal of anesthesiology · 2024Review
- Pancreaticoduodenectomy in patients < 75 years versus ≥ 75 years old: a comparative study.Aging clinical and experimental research · 2024Article
- Prehabilitation approaches for gastrointestinal cancer surgery: a narrative review.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2024Review
- Frailty: the perioperative and anesthesia challenges of an emerging pandemic.Journal of anesthesia · 2023Review
- Frailty in Very Elderly Patients is Not Associated with Adverse Surgical or Oncological Outcomes in Extremity Surgery for Soft Tissue Sarcoma.Annals of surgical oncology · 2022Article
- Prevalence of Frailty among Community-Dwelling Older Adults in Asian Countries: A Systematic Review and Meta-Analysis.Healthcare (Basel, Switzerland) · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFrailty has been generally been associated with adverse events in older patients under surgery. Frailty phenotype is the most widely used instrument in the research literature. However the effect of the frailty phenotype on post-operative events was still unclear. The purpose of this systematic review was to explore the association between frailty phenotype and post-operative complications among surgical patients aged 60 years and over.
methodsRelevant studies were identified by systematically searching of PubMed, Embase, the Cochrane Library and the Web of Science databases from their beginning to March 2017. Both random-effects models and fixed-effects models were used to combine the risk ratios (RRs) and 95% confidence intervals (CIs). A subgroup analysis was performed to identify the sources of heterogeneity and a sensitivity analysis to identify the strength of the results.
resultsTwelve prospective cohort studies involving a total of 2278 patients were included. The risk of post-operative complications in the frail group was higher than the non-frail group (RR: 1.6; 95% CI: 1.60-2.13). Compared with the robust group, geriatric patients with frailty or pre-frailty had a higher risk of post-operative complications. The RRs were 1.77 (95% CI: 1.40-2.25) and 1.45 (95% CI: 1.17-1.80), respectively.
conclusionFrailty phenotype should be considered as a useful risk assessment tool for preoperative evaluations of geriatric patients by medical staff.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.