ArticleBMC geriatrics2019
Body weight, frailty, and chronic pain in older adults: a cross-sectional study.
Article in BMC geriatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed, 66 citations in OpenAlex.
- Chronic Pain in Older Adults: Risk Factors and Prevention.Life (Basel, Switzerland) · 2026Review
- Long-Term Opioids in Gout: A Matched Cohort Study From the Veterans Health Administration.Arthritis care & research · 2026Article
- Association between body mass index and pain outcomes in elderly patients with chronic pain: A retrospective cohort study.Journal of anesthesia · 2026Article
- Association Between the Frailty Index and Self-Reported Headache in Middle-Aged and Older Chinese Adults: An Analysis of the China Health and Retirement Longitudinal Study.Pain research & management · 2026Article
- Quality of life after pulmonary embolism: psychometric validation of the Danish electronic version of the PEmb-QoL questionnaire.BMJ open · 2025Article
- The association between frailty index and all-cause mortality in US individuals with kidney stones: mediation by systemic immune-inflammation (SII) index.Urolithiasis · 2025Article
- Assessing Functional Independence and Associated Factors in Older Populations of Kazakhstan: Implications for Long-Term Care.Healthcare (Basel, Switzerland) · 2025Article
- Trends and inequalities in obesity and thinness among Chinese older adults based on CLHLS.Scientific reports · 2025Article
- Where Does It Hurt? A 4-S Model of Pain Onset and Recovery Across Body Sites Among Older Adults.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025Article
- Inflammatory parameters mediates the relationship between dietary index for gut microbiota and frailty in middle-aged and older adults in the United States: findings from a large-scale population-based study.Frontiers in nutrition · 2025Article
- Bidirectional causal associations between frailty measures and sleep disturbances: a two-sample Mendelian randomization study.Nature and science of sleep · 2025Article
- Relationships between orofacial pain and sleep: Analysis of UK biobank and genome-wide association studies data.Journal of dental sciences · 2025Article
- Factors Associated with Frailty in Older Adults in Community and Nursing Home Settings: A Systematic Review with a Meta-Analysis.Journal of clinical medicine · 2024Review
- The association of painful and non-painful morbidities with frailty: a cross sectional analysis of a cohort of community dwelling older people in England.BMC geriatrics · 2024Article
- Body composition and body mass index are independently associated with widespread pain and experimental pain sensitivity in older adults: a pilot investigation.Frontiers in pain research (Lausanne, Switzerland) · 2024Article
- Association of frailty and serum neurofilament light chain levels: the mediating role of estimated glomerular filtration rate.Frontiers in aging neuroscience · 2024Article
- Bidirectional causal relational between frailty and mental illness: a two-sample Mendelian randomization study.Frontiers in psychiatry · 2024Article
- A genome-wide association study of frailty identifies significant genetic correlation with neuropsychiatric, cardiovascular, and inflammation pathways.GeroScience · 2023Article
- Trends of underweight, overweight, and obesity among older adults in China from 2008 to 2018: a national observational survey.BMC public health · 2023Observational
- eHealth in obesity care.Clinical medicine (London, England) · 2023Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundThere exists limited data on the association between unhealthy body weight and chronic pain, and whether this association is explained by frailty status of older adults.
methodsWe included older adults aged ≥65 years from the 1999-2004 National Health and Nutrition Examination Survey (NHANES). Chronic pain was defined by self-reported pain lasting for ≥3 months in the past year. Body mass index (BMI) was categorized as underweight, normal, overweight, and obese. Participants were dichotomized as frail or non-frail based on a validated frailty index calculated as the proportion of the number of deficits present to a total of 45 possible deficits ascertained in NHANES. We used modified Poisson regression models to estimate prevalence ratios (PRs) and their 95% confidence intervals (CIs).
resultsOf 3693 older participants, one in six (15.9%) experienced chronic pain, with higher prevalence among the underweight (24.6%) and obese (20.2%) group. Frailty versus non-frailty was independently associated with BMI (PR = 1.25, 95% CI = 1.16-1.36 for underweight; and PR = 1.15, 95% CI = 1.07-1.22 for obese), and chronic pain (PR = 2.84, 95% CI = 2.18-3.69). After adjustment for frailty, the association between BMI and chronic pain decreased from PR = 1.82 to 1.64 for the underweight and 1.41 to 1.33 for the obese group. We did not observe an interaction effect between frailty and BMI.
conclusionsUnhealthy body weight was associated with increased chronic pain and the associations were partially explained by frailty status of older adults. Our findings generate hypotheses for further investigations of the interplay of these chronic conditions in older adults.
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