ArticleJournal of dental research2019
Effect of Sustained Joint Loading on TMJ Disc Nutrient Environment.
Article in Journal of dental research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 33 citations in OpenAlex.
- Dynamic Mechanics and Longitudinal Changes in Temporomandibular Joint Structural Integrity.Journal of oral rehabilitation · 2026Article
- Bridging Temporomandibular Joint Structure, Function, and Pain: An Integrated Multiscale Perspective.Journal of dental research · 2026Review
- Preclinical perspectives on disorders of the temporomandibular joint: Tracing the past, navigating the present, and shaping the future.The journal of pain · 2025Review
- The challenge of ecological validity in temporomandibular disorders research.Journal of oral rehabilitation · 2025Review
- Effect of temporomandibular joint anterior disc displacement on condylar height in different age groups.BMC oral health · 2025Article
- Finite element analysis of SED and facial morphology.BMC oral health · 2025Observational
- Different effects of abnormal mechanical stress on temporomandibular joint cartilage, subchondral bone, and discs.Frontiers in physiology · 2025Review
- Biomechanical effects of functional clear aligners on the stomatognathic system in teens with class II malocclusion: a new model through finite element analysis.BMC oral health · 2024Article
- Mechanics- and Behavior-Related Temporomandibular Joint Differences.Journal of dental research · 2024Observational
- Viable Vitreous Grafts of Whole Porcine Menisci for Transplant in the Knee and Temporomandibular Joints.Advanced healthcare materials · 2024Article
- Explainable deep learning and biomechanical modeling for TMJ disorder morphological risk factors.JCI insight · 2024Article
- Critical signaling molecules in the temporomandibular joint osteoarthritis under different magnitudes of mechanical stimulation.Frontiers in pharmacology · 2024Review
- 3D printing materials and 3D printed surgical devices in oral and maxillofacial surgery: design, workflow and effectiveness.Regenerative biomaterials · 2024Review
- Effects of glucose concentration and oxygen partial pressure on the respiratory metabolism of sheep temporomandibular joint disc cells.Experimental and therapeutic medicine · 2023Article
- Effects of the advanced mandibular spring on mandibular retrognathia treatment: a three-dimensional finite element study.BMC oral health · 2022Article
- Effect of facet inclination and location on TMJ loading during bruxism: AnJournal of advanced research · 2022Article
- The effect of tooth cusp morphology and grinding direction on TMJ loading during bruxism.Frontiers in physiology · 2022Article
- Clinical variables associated with the presence of articular pain in patients with temporomandibular joint clicking.Clinical oral investigations · 2021Article
- Age-related changes in the cartilage of the temporomandibular joint.GeroScience · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 5 institutions in 2 countries.
Funding
Abstract
The temporomandibular joint (TMJ) disc nutrient environment profoundly affects cell energy metabolism, proliferation, and biosynthesis. Due to technical challenges of in vivo measurements, the human TMJ disc extracellular nutrient environment under load, which depends on metabolic rates, solute diffusion, and disc morphometry, remains unknown. Therefore, the study objective was to predict the TMJ disc nutrient environment under loading conditions using combined experimental and computational modeling approaches. Specifically, glucose consumption and lactate production rates of porcine TMJ discs were measured under varying tissue culture conditions (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.