Evidence map›Paper›PMID 31126084›Full record

ArticleNanomaterials (Basel, Switzerland)2019

Interaction between Copper Oxide Nanoparticles and Amino Acids: Influence on the Antibacterial Activity.

Elena Badetti, Loris Calgaro, Laura Falchi, Alessandro Bonetto, Cinzia Bettiol, Benedetta Leonetti, Emmanuele Ambrosi, Elisabetta Zendri, Antonio Marcomini

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Metallic nanoparticles: a promising novel therapeutic tool against antimicrobial resistance and spread of superbugs.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2025
    Review
  6. Review
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Elena BadettiDAIS-Department of Environmental Sciences, Informatics and Statistics, University Ca' Foscari of Venice, Via Torino 155, 30172 Venice Mestre, Italy. elena.badetti@unive.it.ORCID 0000-0002-3984-7829
Loris CalgaroDAIS-Department of Environmental Sciences, Informatics and Statistics, University Ca' Foscari of Venice, Via Torino 155, 30172 Venice Mestre, Italy. loris.calgaro@unive.it.ORCID 0000-0001-7492-2700
Laura FalchiDAIS-Department of Environmental Sciences, Informatics and Statistics, University Ca' Foscari of Venice, Via Torino 155, 30172 Venice Mestre, Italy. laura.falchi@unive.it.
Alessandro BonettoDAIS-Department of Environmental Sciences, Informatics and Statistics, University Ca' Foscari of Venice, Via Torino 155, 30172 Venice Mestre, Italy. alessandro.bonetto@unive.it.ORCID 0000-0002-1642-2553
Cinzia BettiolDAIS-Department of Environmental Sciences, Informatics and Statistics, University Ca' Foscari of Venice, Via Torino 155, 30172 Venice Mestre, Italy. bettiol@unive.it.
Benedetta LeonettiDMSN-Department of Molecular Sciences and Nanosystems, University Ca' Foscari of Venice, Via Torino 155/b, 30172 Venice Mestre, Italy. leonetti393@gmail.com.ORCID 0000-0002-3743-3913
Emmanuele AmbrosiDMSN-Department of Molecular Sciences and Nanosystems, University Ca' Foscari of Venice, Via Torino 155/b, 30172 Venice Mestre, Italy. emmanuele.kizito@gmail.com.
Elisabetta ZendriDAIS-Department of Environmental Sciences, Informatics and Statistics, University Ca' Foscari of Venice, Via Torino 155, 30172 Venice Mestre, Italy. elizen@unive.it.
Antonio MarcominiDAIS-Department of Environmental Sciences, Informatics and Statistics, University Ca' Foscari of Venice, Via Torino 155, 30172 Venice Mestre, Italy. marcom@unive.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increasing concern about antibiotic-resistance has led to the search for alternative antimicrobial agents. In this effort, different metal oxide nanomaterials are currently under investigation, in order to assess their effectiveness, safety and mode of action. This study focused on CuO nanoparticles (CuO NPs) and was aimed at evaluating how the properties and the antimicrobial activity of these nanomaterials may be affected by the interaction with ligands present in biological and environmental media. Ligands can attach to the surface of particles and/or contribute to their dissolution through ligand-assisted ion release and the formation of complexes with copper ions. Eight natural amino acids (L-Arg, L-Asp, L-Glu, L-Cys, L-Val, L-Leu, L-Phe, L-Tyr) were chosen as model molecules to investigate these interactions and the toxicity of the obtained materials against the Gram-positive bacterium

Indexed as

amino acidsantimicrobial activitycopper oxide nanoparticles

Identifiers

PMID31126084
PMCPMC6566567

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.