Evidence map›Paper›PMID 31126029›Full record

ArticleInternational journal of molecular sciences2019

Transcriptome Analysis to Shed Light on the Molecular Mechanisms of Early Responses to Cadmium in Roots and Leaves of King Grass (

Junming Zhao, Bo Xia, Yu Meng, Zhongfu Yang, Ling Pan, Man Zhou, Xinquan Zhang

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
14.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 56 citations in OpenAlex.

  1. Article
  2. Effects of compound fermentation withFrontiers in veterinary science · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Unraveling Cadmium Toxicity inInternational journal of molecular sciences · 2022
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Effects of Citric Acid andFrontiers in microbiology · 2021
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Junming ZhaoDepartment of Grassland Science, Sichuan Agricultural University, Chengdu 611130, China. junmingzhao163@163.com.
Bo XiaDepartment of Genetics and Biochemistry, Clemson University, Clemson, SC 29634-0318, USA. bxia@g.clemson.edu.
Yu MengCollege of Natural, Applied and Health Sciences, Wenzhou Kean University, Wenzhou 325060, China. meng.yoyo@wku.edu.cn.
Zhongfu YangDepartment of Grassland Science, Sichuan Agricultural University, Chengdu 611130, China. yangzf211@163.com.
Ling PanDepartment of Grassland Science, Sichuan Agricultural University, Chengdu 611130, China. panling1199@126.com.
Man ZhouCollege of Natural, Applied and Health Sciences, Wenzhou Kean University, Wenzhou 325060, China. Man.Zhou.Research@gmail.com.
Xinquan ZhangDepartment of Grassland Science, Sichuan Agricultural University, Chengdu 611130, China. zhangxq@sicau.edu.cn.
Sichuan Agricultural University · CNWenzhou-Kean University · CNClemson University · US

Funding

Sichuan Province Science and Technology Support Program No.2019YFH0064the earmarked fund for Modern Agro-industry Technology Research System No.CARS-34
6 · The paper itself

Abstract

King grass, a hybrid grass between pearl millet and elephant grass, has many excellent characteristics such as high biomass yield, great stress tolerance, and enormous economic and ecological value, which makes it ideal for development of phytoremediation. At present, the physiological and molecular response of king grass to cadmium (Cd) stress is poorly understood. Transcriptome analysis of early response (3 h and 24 h) of king grass leaves and roots to high level Cd (100 µM) has been investigated and has shed light on the molecular mechanism underlying Cd stress response in this hybrid grass. Our comparative transcriptome analysis demonstrated that in combat with Cd stress, king grass roots have activated the glutathione metabolism pathway by up-regulating glutathione S-transferases (GSTs) which are a multifunctional family of phase II enzymes that detoxify a variety of environmental chemicals, reactive intermediates, and secondary products of oxidative damages. In roots, early inductions of phenylpropanoid biosynthesis and phenylalanine metabolism pathways were observed to be enriched in differentially expressed genes (DEGs). Meanwhile, oxidoreductase activities were significantly enriched in the first 3 h to bestow the plant cells with resistance to oxidative stress. We also found that transporter activities and jasmonic acid (JA)-signaling might be activated by Cd in king grass. Our study provided the first-hand information on genome-wide transcriptome profiling of king grass and novel insights on phytoremediation.

Indexed as

Gene Expression Regulation, PlantTranscriptomeCadmiumGene Expression ProfilingGlutathione TransferasePennisetumPlant LeavesPlant ProteinsPlant RootsStress, PhysiologicalCadmiumGlutathione TransferasePlant ProteinsCd responsesdifferentially expressed genesmolecular mechanismPennisetum americanum × P. purpureumtranscriptome

Identifiers

PMID31126029
PMCPMC6567004
OpenAlexW2946814444

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.