Evidence map›Paper›PMID 31125537›Full record

ArticleJournal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons2019

Temporomandibular Joint Condyle-Disc Morphometric Sexual Dimorphisms Independent of Skull Scaling.

Matthew C Coombs, Xin She, Truman R Brown, Elizabeth H Slate, Janice S Lee, Hai Yao

Open access · greenAbstract read
In one paragraph

Article in Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. [Cone-beam CT evaluation of temporomandibular joint in skeletal class Ⅱ female adolescents with different vertical patterns].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Matthew C CoombsPostdoctoral Fellow, Department of Bioengineering, Clemson University, Clemson, SC; and Department of Oral Health Sciences, Medical University of South Carolina, Charleston, SC.
Xin SheGraduate Assistant, Department of Bioengineering, Clemson University, Clemson, SC.
Truman R BrownProfessor, Center for Biomedical Imaging, Medical University of South Carolina, Charleston, SC.
Elizabeth H SlateProfessor, Department of Statistics, Florida State University, Tallahassee, FL.
Janice S LeeClinical Director, National Institutes of Health National Institute of Dental and Craniofacial Research, Bethesda, MD.
Hai YaoProfessor, Department of Bioengineering, Clemson University, Clemson, SC; and Department of Oral Health Sciences, Medical University of South Carolina, Charleston, SC. Electronic address: haiyao@clemson.edu.
Clemson University · USFlorida State University · USMedical University of South Carolina · USNational Institutes of Health · US

Funding

Tissue Structural and Neural Remodeling in Human Sacroiliac JointP20GM121342 · NIGMS · CLEMSON UNIVERSITY · PI Hai Yao · 2018 to 2026
$24.7M
Craniofacial Anomalies and RegenerationZIADE000746 · NIDCR · NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH · PI LEE, JANICE · 2015 to 2025
$12.3M
T-COHR: Training in Craniofacial and Oral Health ResearchT32DE017551 · NIDCR · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI YAO, HAI · 2006 to 2025
$10.3M
Integrating craniofacial morphology, oral function, temporomandibular biomechanics and mechanobiology to determine sex-specific TMJ pathophysiology in humansR01DE021134 · NIDCR · CLEMSON UNIVERSITY · PI YAO, HAI · 2012 to 2025
$4.7M
Biophysical Modeling of Fluid and Solute Transport in the TMJ DiscR03DE018741 · NIDCR · CLEMSON UNIVERSITY · PI YAO, HAI · 2009 to 2010
$223k
Structure-function relationships between human temporomandibular lateral capsule-ligament complex tensile stiffness, collagen ultrastructure and ECM composition: Investigation of sexual dimorphismsF32DE027864 · NIDCR · CLEMSON UNIVERSITY · PI COOMBS, MATTHEW CHATTERJEE · 2018 to 2018
$40k
NIDCR NIH HHS F32 DE027864NIDCR NIH HHS R01 DE021134NIDCR NIH HHS R03 DE018741NIDCR NIH HHS T32 DE017551NIGMS NIH HHS P20 GM121342
6 · The paper itself

Abstract

purposeApproximately 2 to 4% of the US population have been estimated to seek treatment for temporomandibular symptoms, predominately women. The study purpose was to determine whether sex-specific differences in temporomandibular morphometry result from scaling with sex differences in skull size and shape or intrinsic sex-specific differences. MATERIALS AND

methodsA total of 22 (11 male [aged 74.5 ± 9.1 years]; 11 female [aged 73.6 ± 12.8 years]) human cadaveric heads with no history of temporomandibular disc derangement underwent cone beam computed tomography and high-resolution magnetic resonance imaging scanning to determine 3-dimensional cephalometric parameters and temporomandibular morphometric outcomes. Regression models between morphometric outcomes and cephalometric parameters were developed, and intrinsic sex-specific differences in temporomandibular morphometry normalized by cephalometric parameters were determined. Subject-specific finite element (FE) models of the extreme male and extreme female conditions were developed to predict variations in articular disc stress-strain under the same joint loading.

resultsIn some cases, sex differences in temporomandibular morphometric parameters could be explained by linear scaling with skull size and shape; however, scaling alone could not fully account for some differences between sexes, indicating intrinsic sex-specific differences. The intrinsic sex-specific differences in temporomandibular morphometry included an increased condylar medial length and mediolateral disc lengths in men and a longer anteroposterior disc length in women. Considering the extreme male and female temporomandibular morphometry observed in the present study, subject-specific FE models resulted in sex differences, with the extreme male joint having a broadly distributed stress field and peak stress of 5.28 MPa. The extreme female joint had a concentrated stress field and peak stress of 7.37 MPa.

conclusionsIntrinsic sex-specific differences independent of scaling with donor skull size were identified in temporomandibular morphometry. Understanding intrinsic sex-specific morphometric differences is critical to determining the temporomandibular biomechanics given the effect of anatomy on joint contact mechanics and stress-strain distributions and requires further study as one potential factor for the increased predisposition of women to temporomandibular disc derangement.

Indexed as

Joint DislocationsTemporomandibular JointTemporomandibular Joint DiscAgedAged, 80 and overCadaverFemaleHumansMagnetic Resonance ImagingMaleMandibular CondyleMiddle AgedSex CharacteristicsSkull

Identifiers

PMID31125537
PMCPMC6814518
OpenAlexW2941442986

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.