ArticleJournal of cachexia, sarcopenia and muscle2019
Associations between sleep conditions and body composition states: results of the EPISONO study.
Article in Journal of cachexia, sarcopenia and muscle, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05159141 (The Role of Circadian Rhythm in the Effect of Sleep Intervention on Obesity Prevention in Early Childhood), which is not on this map. Cited by 32 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Role of Circadian Rhythm in the Effect of Sleep Intervention on Obesity Prevention in Early Childhood
Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.
- The association between obstructive sleep apnea syndrome and sarcopenia: a meta-analysis.Frontiers in medicine · 2026Pooled it
- Trial
- Resistance Training Improves Sleep and Anti-Inflammatory Parameters in Sarcopenic Older Adults: A Randomized Controlled Trial.International journal of environmental research and public health · 2022Trial
- Sleep disturbances, inflammation, and muscle function in older adults with sarcopenia.Sleep & breathing = Schlaf & Atmung · 2026Article
- Expert consensus on osteoporosis risk management in patients with sleep disorders.Bone research · 2026Review
- Sarcopenia and Physical Function in Obstructive Sleep Apnea: A Single-Centre Cross-Sectional Study (The SOSA Study).The clinical respiratory journal · 2026Article
- Causal Links Between Sleep Duration and Sarcopenia-Related Phenotypes: A Mendelian Randomization and Shared Genetic Mechanism Study.American journal of physical medicine & rehabilitation · 2026Article
- The role of sleep disorders in the motoric and cognitive trajectories of older physically frail sarcopenic and healthy active subjects: SOMNUS-DARE, a prospective cohort study.BMC geriatrics · 2026Article
- Identification of shared biomarkers for obstructive sleep apnea and sarcopenia via differential expression and WGCNA analysis.Sleep & breathing = Schlaf & Atmung · 2026Article
- The association between obstructive sleep apnea and frailty traits: a bidirectional Mendelian randomization study.BMC pulmonary medicine · 2026Article
- Sleep Architecture, Muscle Function, and Daily Life Activities in Patients with Sarcopenia.Sleep science (Sao Paulo, Brazil) · 2025Article
- Genetic determinants of muscle health: A population-based study.The Journal of frailty & aging · 2025Article
- Causal associations between Sarcopenia-related traits and obstructive sleep apnea: a mendelian randomization study.Aging clinical and experimental research · 2025Article
- Evaluation of five questionnaires for obstructive sleep apnea screening in the elderly.Scientific reports · 2025Article
- The influence of sex on sleep characteristics in the adult and older adult population: findings from the EPISONO sleep study.Frontiers in sleep · 2025Article
- Associations of Obstructive Sleep Apnea Risk with Obesity, Body Composition and Metabolic Abnormalities in School-Aged Children and Adolescents.Nutrients · 2024Article
- Obstructive sleep apnea (OSA) is associated with increased risk of early-onset sarcopenia and sarcopenic obesity: Results from NHANES 2015-2018.International journal of obesity (2005) · 2024Article
- Progression of obstructive sleep apnoea after renal denervation is not associated with hypertension exaggeration.BMC pulmonary medicine · 2023Observational
- The Modulation of Adipokines, Adipomyokines, and Sleep Disorders on Carcinogenesis.Journal of clinical medicine · 2023Review
- The molecular link between obstructive sleep apnea and osteoarthritis: based on bioinformatics analysis and experimental validation.American journal of translational research · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEvidence suggests anthropometric indicators of obesity are associated with changes in sleep quality and quantity, and the presence of obstructive sleep apnoea (OSA). Investigations including diverse and objective evaluations of sleep and body composition are scarce. We aimed to evaluate the associations between indicators of sleep impairment and body composition states in a sample from a population-based study.
methodsParticipants of the first follow-up of the EPISONO (São Paulo, Brazil) >50 years were cross-sectionally evaluated. Sleep was assessed through questionnaires, actigraphy, and polysomnography. Body composition was evaluated by bioelectrical impedance analysis. Appendicular skeletal muscle mass adjusted for body mass index defined sarcopenia (men <0.789 and women <0.512). Total body fat defined obesity (men >30% and women >40%). The overlap between both conditions defined sarcopenic obesity (SO). Final results were obtained by multinomial logistic regression analysis.
resultsThree hundred fifty-nine adults [mean (standard deviation) age, 61 (8.8) years; 212 (59.1%) female] were enrolled. Obesity was detected in 22.6% of the sample, sarcopenia in 5.6%, and SO in 16.2%. After controlling for covariates, OSA was associated with SO [odds ratio = 3.14, 95% confidence interval (CI) = 1.49-6.61]. Additionally, nocturnal hypoxaemia was associated with both obesity (adjusted odds ratio = 2.59, 95% CI = 1.49-4.49) and SO (odds ratio = 2.92, 95% CI = 1.39-6.13). Other indicators of poor sleep/sleep disorders were not associated with body composition states.
conclusionsSarcopenic obesity but not obesity alone was associated with OSA. Both obesity and SO but not sarcopenia were associated with nocturnal hypoxaemia. The findings suggest a complex pathophysiologic relationship between adverse body composition states and OSA. Upcoming research on risk factors and therapeutic interventions for OSA should target synchronically the lean and adipose body tissues.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.