Evidence map›Paper›PMID 31125013›Full record

ReviewActa bio-medica : Atenei Parmensis2019

Herpes Simplex Virus 1 encephalitis with normal cerebrospinal fluid after brain radiotherapy in a patient with glioblastoma. A case report and review of literature.

Carlotta Mutti, Erica Curti, Rosario Ciliento, Andrea Melpignano, Irene Florindo, Lucia Zinno, Enrico Sasso, Liborio Parrino, Giovanni Pavesi, Anna Elisabetta Vaudano

Abstract readCase ReportsReview
In one paragraph

Review in Acta bio-medica : Atenei Parmensis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Carlotta MuttiNeurology Department, Parma Hospital. carlotta.mutti88@gmail.com.
Erica Curti
Rosario Ciliento
Andrea Melpignano
Irene Florindo
Lucia Zinno
Enrico Sasso
Liborio Parrino
Giovanni Pavesi
Anna Elisabetta Vaudano
University Hospitals Parma Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herpes simplex virus encephalitis (HSE) is the most common cause of letal encephalitis and its prevalence appears higher among oncologic patients who undergo brain radiotherapy (RT). We describe a case of 76-year-old woman with glioblastoma multiforme (GBM) who developed HSE shortly after brain RT. Cerebrospinal fluid analysis (CSF) was normal and the diagnosis was driven by brain MRI and EEG. Prompt introduction of antiviral therapy improved the clinical picture. We highlight the importance of EEG and brain MRI for the diagnosis and suggest the possibility of antiviral profilaxys in oncologic patients who undergo brain RT.

Indexed as

AcyclovirAgedBrain NeoplasmsCranial IrradiationElectroencephalographyEncephalitis, Herpes SimplexFemaleGlioblastomaHerpesvirus 1, HumanHumansMagnetic Resonance ImagingPrognosisRisk AssessmentTreatment OutcomeAcyclovir

Identifiers

PMID31125013
PMCPMC6776207
OpenAlexW2988790749

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.