Evidence map›Paper›PMID 31124743›Full record

ArticleHuman vaccines & immunotherapeutics2019

Evolution of P[8], P[4], and P[6] VP8* genes of human rotaviruses globally reported during 1974 and 2017: possible implications for rotavirus vaccines in development.

Daniel E Velasquez, Baoming Jiang

Open access · bronzeAbstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. The Rotavirus Vaccine Landscape, an Update.Pathogens (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Daniel E VelasquezDivision of Viral Diseases, Centers for Diseases Control and Prevention, Atlanta, GA, USA.ORCID 0000-0001-6520-5777
Baoming JiangDivision of Viral Diseases, Centers for Diseases Control and Prevention, Atlanta, GA, USA.
Centers for Disease Control and Prevention · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-replicating parenteral rotavirus (RV) vaccine candidates are in development in an attempt to overcome the lower efficacy and effectiveness of oral RV vaccines in low-income countries. One of the leading candidates is a truncated recombinant VP8* protein, expressed in

Indexed as

Evolution, MolecularAmino Acid SequenceGenotypeHumansPhylogenyRNA-Binding ProteinsRotavirusRotavirus InfectionsRotavirus VaccinesSequence Analysis, DNAVaccines, SubunitViral Nonstructural ProteinsNS35 protein, rotavirusRNA-Binding ProteinsRotavirus VaccinesVaccines, SubunitViral Nonstructural ProteinsdiarrheadiversityevolutiongenotypeprotectionP typeRotavirusvaccineVP4VP8* protein

Identifiers

PMID31124743
PMCPMC6930099
OpenAlexW2946288100

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.