Evidence map›Paper›PMID 31124539›Full record

ArticleIndian journal of ophthalmology2019

Intravenous tocilizumab in idiopathic pediatric uveitis with refractory cystoid macular edema - A case report.

Kalpana Babu, Bhagya Sudheer, Anand P Rao

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Indian journal of ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Observational
  3. Tocilizumab for Non-Infectious Uveitis: A Systematic Review.Journal of inflammation research · 2025
    Review
  4. Article
  5. An anchoring molecule increases intravitreal retention of antibody-based therapeutics used in the treatment of ocular diseases.Journal of controlled release : official journal of the Controlled Release Society · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Kalpana BabuDepartment of Uveitis and Ocular Inflammation, Vittala International Institute of Ophthalmology and Prabha Eye Clinic and Research Centre, Bengaluru, Karnataka, India.
Bhagya SudheerDepartment of Uveitis and Ocular Inflammation, Vittala International Institute of Ophthalmology and Prabha Eye Clinic and Research Centre, Bengaluru, Karnataka, India.
Anand P RaoDepartment of Pediatric Rheumatology, Manipal Hospitals, Bengaluru, Karnataka, India.
Manipal Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 13-year-old boy with a 4-year history of idiopathic pediatric uveitis and recurrent uveitic macular edema had failed conventional immunomodulatory therapy and presented to us with a vision of 6/24 [right eye (OD)] and 6/9 [left eye (OS)]. Fluorescein angiography showed diffuse vascular leakage along with cystoid macular edema (CME). Intravenous tocilizumab (10 mg/kg body) was given as 14 injections over 12 months. Repeat fluorescein angiography every 3 months showed a dramatic improvement in the vascular leakage and resolution of CME. At 13 months OF follow-up, vision had improved to 6/9p (OD) and 6/6(OS) with no recurrence of inflammation or CME.

Indexed as

AdolescentAntibodies, Monoclonal, HumanizedFluorescein AngiographyFollow-Up StudiesFundus OculiHumansInjections, IntravenousMacula LuteaMacular EdemaMaleTomography, Optical CoherenceUveitisVisual AcuityAntibodies, Monoclonal, HumanizedtocilizumabBiologicscystoid macular edemaidiopathicpediatric uveitistocilizumab

Identifiers

PMID31124539
PMCPMC6552592
OpenAlexW2946916064

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.