Evidence map›Paper›PMID 31124496›Full record

Observational studyIndian journal of ophthalmology2019

Neonatal Intensive Care Unit-based screening program for retinopathy of prematurity and its treatment in an Indian population.

Anubhav Goyal, Ananthraman Giridhar, Mahesh Gopalakrishnan, Thomas Thachil

Open access · diamondAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Indian journal of ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Anubhav GoyalDepartment of Vitreo-Retina, Giridhar Eye Institute, Kochi, Kerala, India.
Ananthraman GiridharDepartment of Vitreo-Retina, Giridhar Eye Institute, Kochi, Kerala, India.
Mahesh GopalakrishnanDepartment of Vitreo-Retina, Giridhar Eye Institute, Kochi, Kerala, India.
Thomas ThachilDepartment of Vitreo-Retina, Giridhar Eye Institute, Kochi, Kerala, India.
Chaithanya Eye Hospital and Research Institute · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The purpose was to study the incidence, risk factors, and anatomical outcomes after laser treatment in retinopathy of prematurity (ROP). Methods: A retrospective observational study was carried out. Infants admitted to Neonatal Intensive Care Unit of 12 referral hospitals between April 2016 and September 2017 were screened according to the latest Indian guidelines based on the International Classification of Retinopathy of Prematurity. Results: The incidence of ROP in 1648 eyes screened was 25.36% (418 eyes), out of which high-risk prethreshold ROP (type 1) was observed in 9.95% (164 eyes). Decreased hemoglobin (P < 0.001), oxygen requirement (P = 0.008), and number of blood transfusions (P = 0.037) were significant with type 1 than type 2 (low-risk prethreshold) ROP. Stages 1, 2, and 3 were observed in 82 (32.28%), 154 (60.62%), and 18 (7.08%) eyes, respectively. Aggressive posterior ROP (APROP) was observed in 20.73% eyes with type 1 ROP. Ten eyes showing APROP were treated at an early gestational age of 29 weeks. All infants with type 1 ROP were treated with laser photocoagulation only. Conclusion: One-fourth of the infants showed ROP and one-tenth needed laser photocoagulation, the outcome of which was excellent. Risk factors predisposing to ROP were anemia, high oxygen supplementation, increased number of blood transfusions, and septicemia. ROP screening in infants ≥1700 g birth weight associated with various systemic risk factors may be beneficial in the Indian population.

Indexed as

Intensive Care Units, NeonatalVisual AcuityFemaleGestational AgeHumansIncidenceIndiaInfant, NewbornLaser CoagulationMaleNeonatal ScreeningOphthalmoscopyRetinopathy of PrematurityRetrospective StudiesRisk FactorsTreatment OutcomeEarly treatment of retinopathy of prematurityhigh-risk prethreshold or type 1 retinopathy of prematurityInternational Classification of Retinopathy of Prematuritylow-risk prethreshold or type 2 retinopathy of prematurityNeonatal Intensive Care Unit

Identifiers

PMID31124496
PMCPMC6552612
OpenAlexW2947977372

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.