Evidence map›Paper›PMID 31124414›Full record

ArticlePharmacogenomics2019

Between a rock and a hard place: a high-risk patient with resistance to multiple P2Y

Brittney H Davis, Chrisly Dillon, Anping Cai, Lance A Williams Iii, Salpy V Pamboukian, Nita A Limdi

Abstract readCase Reports
In one paragraph

Article in Pharmacogenomics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Brittney H DavisDepartment of Neurology, School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA 35294.
Chrisly DillonDepartment of Neurology, School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA 35294.
Anping CaiDepartment of Neurology, School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA 35294.
Lance A Williams IiiDepartment of Pathology, Division of Laboratory Medicine, University of Alabama at Birmingham, Birmingham, AL, USA 35249.
Salpy V PamboukianDepartment of Medicine, Division of Cardiovascular Disease, University of Alabama at Birmingham, Birmingham, AL, USA 35242.
Nita A LimdiDepartment of Neurology, School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA 35294.

Funding

Predictors of hemorrhage among patients on direct acting oral anticoagulantsR01HL092173 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LIMDI, NITA A · 2008 to 2023
$10.4M
UAB-HudsonAlpha Genomic Medicine Training ProgramT32HG008961 · NHGRI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Gregory Michael Cooper, Marguerite R Irvin · 2016 to 2026
$2.5M
Patient Oriented Research in Personalized Antithrombotic TherapyK24HL133373 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LIMDI, NITA A · 2016 to 2025
$1.2M
NHGRI NIH HHS T32 HG008961NHLBI NIH HHS K24 HL133373NHLBI NIH HHS R01 HL092173
6 · The paper itself

Abstract

Impaired response to P2Y

Indexed as

AdultBlood PlateletsClopidogrelCytochrome P-450 CYP2B6Cytochrome P-450 CYP2C19FemaleGenotypeHumansPlatelet AggregationPlatelet Aggregation InhibitorsPrasugrel HydrochlorideReceptors, Purinergic P2Y12Ventricular Dysfunction, LeftClopidogrelCYP2B6 protein, humanCYP2C19 protein, humanCytochrome P-450 CYP2B6Cytochrome P-450 CYP2C19P2RY12 protein, humanPlatelet Aggregation InhibitorsPrasugrel HydrochlorideReceptors, Purinergic P2Y12clopidogrelCYP2B6LVADP2Yprasugrelticagrelor

Identifiers

PMID31124414
PMCPMC6563016

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.