ArticleJournal of the American Chemical Society2019
Polymeric "Clickase" Accelerates the Copper Click Reaction of Small Molecules, Proteins, and Cells.
Article in Journal of the American Chemical Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed.
- Catalyst-Free Biotin Conjugation Onto Poly(Styrene-co-Butadiene) Mediated by an Orthogonal Agent Comprising Nitrile N-Oxide and Blocked Isocyanate.Macromolecular rapid communications · 2026Article
- Copper(I)-Anchoring Covalent Organic Polymer for Heterogeneous CuAAC Reaction without Reducing Agents and Copper Leaching.ACS organic & inorganic Au · 2025Article
- Retrosynthetic Design of Dinuclear Copper Enzymes for Azide-Alkyne Cycloaddition via Clickable Noncanonical Amino Acids.Journal of the American Chemical Society · 2025Article
- Tracker Nanocatalyst for Screening of Intracellular Copper-Catalyzed Azide-Alkyne Cycloadditions.Small (Weinheim an der Bergstrasse, Germany) · 2025Article
- Cooperative Photoredox Catalysis Under Confinement.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Article
- Safirinium Fluorescent "Click" Molecular Probes: Synthesis, CuAAC Reactions, and Microscopic Imaging.Molecules (Basel, Switzerland) · 2025Article
- Micellar "Click" Nanoreactors: Spiking Pluronic-Based Micelles with Polymeric Ligands.Macromolecules · 2024Article
- Visible-light-mediated Diels-Alder reactions under single-chain polymer confinement: investigating the role of the crosslinking moiety on catalyst activity.Polymer chemistry · 2024Article
- Effect of Particle Heterogeneity in Catalytic Copper-Containing Single-Chain Polymeric Nanoparticles Revealed by Single-Particle Kinetics.Molecules (Basel, Switzerland) · 2024Article
- Versatile Prepolymer Platform for Controlled Tailoring of Quantum Dot Surface Properties.ACS applied materials & interfaces · 2024Article
- Biomimetic and bioorthogonal nanozymes for biomedical applications.Nano convergence · 2023Review
- GEN-Click: Genetically Encodable Click Reactions for Spatially Restricted Metabolite Labeling.ACS central science · 2023Article
- Orthogonal Supramolecular Assemblies Using Side-Chain Functionalized Helical Poly(isocyanide)s.Macromolecules · 2023Article
- Simultaneously controlling conformational and operational stability of single-chain polymeric nanoparticles in complex media.Chemical communications (Cambridge, England) · 2023Article
- Dual-Bioorthogonal Catalysis by a Palladium Peptide Complex.Journal of medicinal chemistry · 2023Article
- Metal complexes for catalytic and photocatalytic reactions in living cells and organisms.Chemical science · 2023Review
- Spectrally PAINTing a Single Chain Polymeric Nanoparticle at Super-Resolution.Journal of the American Chemical Society · 2022Article
- En Route to Stabilized Compact Conformations of Single-Chain Polymeric Nanoparticles in Complex Media.Macromolecules · 2022Article
- Extracellular Electron Transfer Enables Cellular Control of Cu(I)-Catalyzed Alkyne-Azide Cycloaddition.ACS central science · 2022Article
- Elucidating the Stability of Single-Chain Polymeric Nanoparticles in Biological Media and Living Cells.Biomacromolecules · 2022Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Recent work has shown that polymeric catalysts can mimic some of the remarkable features of metalloenzymes by binding substrates in proximity to a bound metal center. We report here an unexpected role for the polymer: multivalent, reversible, and adaptive binding to protein surfaces allowing for accelerated catalytic modification of proteins. The catalysts studied are a group of copper-containing single-chain polymeric nanoparticles (Cu
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.