Evidence map›Paper›PMID 31124312›Full record

ReviewAmerican journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics2019

International Society of Psychiatric Genetics Ethics Committee: Issues facing us.

Gabriel Lázaro-Muñoz, Maya Sabatello, Laura Huckins, Holly Peay, Franziska Degenhardt, Bettina Meiser, Todd Lencz, Takahiro Soda, Anna Docherty, David Crepaz-Keay and 4 more

Open access · greenAbstract readReview
In one paragraph

Review in American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Return of results in a global survey of psychiatric genetics researchers: practices, attitudes, and knowledge.Genetics in medicine : official journal of the American College of Medical Genetics · 2021
    Article
  9. Article
  10. Pharmacogenetics of Obsessive-Compulsive Disorder: An Evidence-Update.Current topics in behavioral neurosciences · 2021
    Review
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 13 institutions in 5 countries.

Gabriel Lázaro-MuñozBaylor College of Medicine, Houston, Texas.ORCID 0000-0003-1933-9453
Maya SabatelloColumbia University, New York, New York.
Laura HuckinsIcahn School of Medicine at Mount Sinai, New York, New York.
Holly PeayRTI International, Durham, North Carolina.
Franziska DegenhardtUniversity of Bonn, Bonn, Germany.
Bettina MeiserUniversity of New South Wales, Sydney, Australia.
Todd LenczHofstra University, Hempstead, New York.
Takahiro SodaUniversity of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Anna DochertyUniversity of Utah, Salt Lake City, Utah.
David Crepaz-KeayMental Health Foundation, London, UK.
Jehannine AustinUniversity of British Columbia, Vancouver, British Columbia, Canada.
Roseann E PetersonVirginia Commonwealth University, Richmond, Virginia.
Lea K DavisVanderbilt University, Nashville, Tennessee.
ISPG Ethics Committee
Baylor College of Medicine · USColumbia University · USHofstra University · USIcahn School of Medicine at Mount Sinai · USMental Health Foundation · GBRTI International · USUniversity of Bonn · DEUniversity of British Columbia · CAUniversity of North Carolina at Chapel Hill · USUniversity of Utah · USUNSW Sydney · AUVanderbilt University · USVirginia Commonwealth University · US

Funding

Utah Center for Clinical and Translational ScienceUL1TR002538 · NCATS · UNIVERSITY OF UTAH · PI HESS, RACHEL, MAJERSIK, JENNIFER JUHL · 2018 to 2022
$26.0M
Training and Mentoring CoreU54MD010722 · NIMHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI COX, NANCY J · 2016 to 2020
$11.9M
Genetic Privacy and Identity in Community Settings - GetPreCiSeRM1HG009034 · NHGRI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CLAYTON, ELLEN WRIGHT, MALIN, BRADLEY A. · 2016 to 2024
$8.3M
Cognitive Genomics as a Window on Neurodevelopment and PsychopathologyR01MH117646 · NIMH · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI TODD LENCZ · 2018 to 2026
$4.7M
Return of Results from Psychiatric Genomics Research: Attitudes and BarriersR00HG008689 · NHGRI · BAYLOR COLLEGE OF MEDICINE · PI LAZARO-MUNOZ, GABRIEL · 2017 to 2019
$905k
Impact of Psychiatric Genetic Data on Civil Litigation and its Relationship with StigmaK01HG008653 · NHGRI · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI SABATELLO, MAYA · 2015 to 2019
$871k
Modeling Dimensionality and Genetic Heterogeneity in SchizophreniaK01MH109765 · NIMH · VIRGINIA COMMONWEALTH UNIVERSITY · PI DOCHERTY, ANNA R. · 2016 to 2019
$675k
Leveraging sources of heterogeneity to delineate the genetic architecture of major depressive disorderK01MH113848 · NIMH · VIRGINIA COMMONWEALTH UNIVERSITY · PI PETERSON, ROSEANN ELIZABETH · 2018 to 2020
$546k
NCATS NIH HHS UL1 TR002538NHGRI NIH HHS K01 HG008653NHGRI NIH HHS R00 HG008689NHGRI NIH HHS RM1 HG009034NIH HHSNIMHD NIH HHS U54 MD010722NIMH NIH HHS K01 MH109765NIMH NIH HHS K01 MH113848NIMH NIH HHS R01 MH117646
6 · The paper itself

Abstract

Psychiatric genetics research is improving our understanding of the biological underpinnings of neurodiversity and mental illness. Using psychiatric genetics in ways that maximize benefits and minimize harms to individuals and society depends largely on how the ethical, legal, and social implications (ELSI) of psychiatric genetics are managed. The International Society of Psychiatric Genetics (ISPG) is the largest international organization dedicated to psychiatric genetics. Given its history, membership, and international reach, we believe the ISPG is well-equipped to contribute to the resolution of these ELSI challenges. As such, we recently created the ISPG Ethics Committee, an interdisciplinary group comprised of psychiatric genetics researchers, clinical geneticists, genetic counselors, mental health professionals, patients, patient advocates, bioethicists, and lawyers. This article highlights key ELSI challenges identified by the ISPG Ethics Committee to be of paramount importance for the ethical translation of psychiatric research into society in three contexts: research settings, clinical settings, and legal proceedings. For each of these arenas, we identify and discuss pressing psychiatric genetics ELSI dilemmas that merit attention and require action. The goal is to increase awareness about psychiatric genetics ELSI issues and encourage dialogue and action among stakeholders.

Indexed as

Ethics CommitteesGenetic ResearchGenomicsHumansMental DisordersELSIethicsgeneticspsychiatrytesting

Identifiers

PMID31124312
PMCPMC6861601
OpenAlexW2945853979

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.