ArticleJournal of autism and developmental disorders2019
Characteristics Associated with Autism Spectrum Disorder Risk in Individuals with Down Syndrome.
Article in Journal of autism and developmental disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
23 citing papers in PubMed.
- Associations of Down Syndrome with Autism Spectrum Disorder and Attention Deficit/ Hyperactivity Disorder Among Children and Adolescents.Journal of autism and developmental disorders · 2026Article
- Short-term and Long-term Stability of the Autism Diagnostic Observation Schedule (ADOS-2) Calibrated Comparison Scores (CCS) and Classification Scores in Youth with Down Syndrome or Fragile X Syndrome with Intellectual Disability.Journal of autism and developmental disorders · 2026Article
- Autism Among Adults with Down Syndrome: Prevalence, Medicaid Usage, and Co-Occurring Conditions.Journal of autism and developmental disorders · 2025Article
- Prediction of chromosomal abnormalities in the screening of the first trimester of pregnancy using machine learning methods: a study protocol.Reproductive health · 2024Article
- Autism Spectrum Disorder in Down Syndrome: Experiences from Caregivers.Journal of autism and developmental disorders · 2024Article
- Pragmatic competence in people with dual diagnosis: down syndrome and autism spectrum disorder.BMC psychology · 2024Article
- Associations Among Sex, Cognitive Ability, and Autism Symptoms in Individuals with Down Syndrome.Journal of autism and developmental disorders · 2024Article
- Using the Social Skills Improvement System (SSiS) Rating Scales to assess social skills in youth with Down syndrome.Frontiers in psychology · 2023Article
- Heterogeneity of Autism Characteristics in Genetic Syndromes: Key Considerations for Assessment and Support.Current developmental disorders reports · 2023Review
- Sexually dimorphic DYRK1A overexpression on postnatal day 15 in the Ts65Dn mouse model of Down syndrome: Effects of pharmacological targeting on behavioral phenotypes.Pharmacology, biochemistry, and behavior · 2022Article
- Patterns and predictors of adaptive skills in 2- to 7-year-old children with Down syndrome.Journal of neurodevelopmental disorders · 2022Article
- Co-occurring Down Syndrome and Autism Spectrum Disorder: Cognitive, Adaptive, and Behavioral Characteristics.Journal of autism and developmental disorders · 2022Article
- Latent profiles of autism symptoms in children and adolescents with Down syndrome.Journal of intellectual disability research : JIDR · 2022Article
- Prenatal and Postnatal Pharmacotherapy in Down Syndrome: The Search to Prevent or Ameliorate Neurodevelopmental and Neurodegenerative Disorders.Annual review of pharmacology and toxicology · 2022Article
- Symptoms of Autism Spectrum Disorder in Individuals with Down Syndrome.Brain sciences · 2021Article
- Relationship between Apgar scores and long-term cognitive outcomes in individuals with Down syndrome.Scientific reports · 2021Article
- Capturing cognitive and behavioral variability among individuals with Down syndrome: a latent profile analysis.Journal of neurodevelopmental disorders · 2021Article
- Exploring Expressive Communication Skills in a Cross-Sectional Sample of Individuals With a Dual Diagnosis of Autism Spectrum Disorder and Down Syndrome.American journal on intellectual and developmental disabilities · 2021Article
- Abnormalities of synaptic mitochondria in autism spectrum disorder and related neurodevelopmental disorders.Journal of molecular medicine (Berlin, Germany) · 2021Review
- Gestational age is related to symptoms of attention-deficit/hyperactivity disorder in late-preterm to full-term children and adolescents with down syndrome.Scientific reports · 2020Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We examined autism spectrum disorder (ASD) risk in a large national sample of 203 individuals with Down syndrome, 6-25 years old, to determine the association of ASD risk with age, sex, IQ, adaptive behaviors, and maladaptive behaviors. We used a two-pronged approach by (1) considering ASD symptomatology continuously across the sample of individuals with DS and examining associations with each characteristic, and (2) dichotomizing our sample into high and low ASD risk groups and comparing groups on each characteristic. The pattern of results was largely similar across both types of analyses. ASD symptomatology/risk was negatively associated with IQ and adaptive behaviors and positively associated with certain types of maladaptive behaviors. Clinical implications for screening and therapeutic purposes are discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.