ArticleTranslational sports medicine2019
Moderate-intensity aerobic exercise improves skeletal muscle quality in older adults.
Article in Translational sports medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- Muscle Protein Synthesis Responses Following Aerobic-Based Exercise or High-Intensity Interval Training with or Without Protein Ingestion: A Systematic Review.Sports medicine (Auckland, N.Z.) · 2022Pooled it
- Exploring the Association between Vascular Dysfunction and Skeletal Muscle Mass, Strength and Function in Healthy Adults: A Systematic Review.Nutrients · 2020Pooled it
- Effects of 5 Years of Aerobic Exercise on Sarcopenia in Older Adults-Secondary Outcomes of the Generation 100 Study.Journal of cachexia, sarcopenia and muscle · 2026Trial
- Effects of Isolated Soy Protein Supplementation Combined with Aerobic Exercise Training on Improving Body Composition, Anthropometric Characteristics and Cardiopulmonary Endurance in Women: A Pilot Study.International journal of environmental research and public health · 2021Trial
- Low skeletal muscle capillarization limits muscle adaptation to resistance exercise training in older adults.Experimental gerontology · 2019Trial
- Research progress on the diagnosis and pathogenesis of chronic heart failure combined with sarcopenia.Journal of cardiothoracic surgery · 2026Review
- Review
- Protein intake, physical activity, and skeletal muscle outcomes in middle-aged adults: an observational study from the US.Journal of nutritional science · 2026Observational
- Efficacy of simultaneous aerobic and cognitive training (Activ4Brain) on physical fitness and body composition in older persons.Frontiers in aging · 2026Article
- Enhancing physical fitness in older adults: a six-month medium intensity training intervention yields significant improvements.BMC sports science, medicine & rehabilitation · 2025Article
- Episodic denervation as a driver of loss of skeletal muscle redox homeostasis and muscle weakness in sarcopenia: Possible amelioration by exercise.Sports medicine and health science · 2025Review
- Review
- Home-Based Virtual Reality Exercise and Resistance Training for Enhanced Cardiorespiratory Fitness in Community-Dwelling Older People with Sarcopenia: A Randomized, Double-Blind Controlled Trial.Life (Basel, Switzerland) · 2025Article
- Voluntary Exercise-Induced Skeletal Muscle Responses in Young and Aged Mice on a High-Fat Diet.Cureus · 2025Article
- Review
- The effects of resistance training on denervated myofibers, senescent cells, and associated protein markers in middle-aged adults.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024Article
- Differential association between physical activity behaviours and dynapenia by comorbid diseases in community-dwelling Korean older adults.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2024Article
- Musculoskeletal Health Worsened from Carnitine Supplementation and Not Impacted by a Novel Individualized Treadmill Training Protocol.American journal of nephrology · 2024Article
- Factors, mechanisms and improvement methods of muscle strength loss.Frontiers in cell and developmental biology · 2024Review
- Effects of Exercise Training on Muscle Quality in Older Individuals: A Systematic Scoping Review with Meta-Analyses.Sports medicine - open · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
Sarcopenia, age-associated involuntary loss of muscle and strength, can progress to clinically relevant functional decline. Resistance exercise attenuates muscle and strength loss but may not be feasible for some older adults. Aerobic exercise training (AET) improves cardiopulmonary health; however, effects on protein turnover, muscle mass, and strength are less clear. We aimed to determine whether AET improves basal myofibrillar protein synthesis (MPS) and capillarization, promoting hypertrophy and strength. We hypothesized that AET improves strength with increased MPS and capillarization. Older adults were randomized to non-exercise (NON; n = 11, 71.4 ± 4.18 years) or exercise (EX; n = 12, 73.7 ± 4.05 years). EX completed 24 weeks of AET (walking 3×/week, 45 minutes, 70% heart rate reserve); NON remained sedentary. A stable isotope tracer was infused. MPS and capillarization were analyzed from
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.