ArticleSurgical neurology international2019
The pCONUS bifurcation aneurysm implants for endovascular treatment of adults with intracranial aneurysms: A systematic review and meta-analysis.
Article in Surgical neurology international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Endoluminal flow diverters in the treatment of sidewall and bifurcation aneurysm: A systematic review and meta-analysis of complications and angiographic outcomes.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2022Pooled it
- Efficacy and safety of PulseRider for treatment of wide-necked intracranial aneurysm-A systematic review and meta-analysis.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2021Pooled it
- Real-world use of the pEGASUS-HPC stent in cerebral aneurysms: results from a multicenter retrospective series.Neuroradiology · 2026Observational
- Intrasaccular Treatment of Intracranial Aneurysms: A Comprehensive Review.Journal of clinical medicine · 2024Review
- Efficacy of pCONUS Devices in the Management of Intracranial Aneurysms: Outcomes of 190 Patients.Cureus · 2024Review
- Large Single-Center Experience with Short-Term Follow-up of Neqstent-Assisted Coiling.AJNR. American journal of neuroradiology · 2024Article
- [Brain aneurysms treatment with pCONus2 device. Initial experience at IMSS].Revista medica del Instituto Mexicano del Seguro Social · 2023Article
- Four-Year Follow-Up on the First-in-Human Experience With Nautilus Intrasaccular System Assisted Coiling for Unruptured Intracranial Aneurysms.Stroke (Hoboken, N.J.) · 2023Article
- A review of technological innovations leading to modern endovascular brain aneurysm treatment.Frontiers in neurology · 2023Review
- Intrasaccular neck-bridging: A technical note on Nautilus-assisted coiling of wide-necked cerebral aneurysms. Feasibility study, immediate and early angiographic results.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2022Article
- Long-term follow-up of the pCONus device for the treatment of wide-neck bifurcation aneurysms.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2022Article
- The evolution of intracranial aneurysm treatment techniques and future directions.Neurosurgical review · 2022Review
- Comprehensive review of the recent advances in devices for endovascular treatment of complex brain aneurysms.The British journal of radiology · 2022Review
- pCONUS 2 and pCONUS 2-HPC for the treatment of wide-necked intracranial aneurysms: Periprocedural, 6-month, and early 2-year follow-up outcomes.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2021Article
- eCLIPs bifurcation remodeling system for treatment of wide neck bifurcation aneurysms with extremely low dome-to-neck and aspect ratios: a multicenter experience.Journal of neurointerventional surgery · 2021Article
- Massively calcified aneurysm of the anterior communicating artery: an unsuccessful clipping attempt followed by successful pCONus2-assisted coil occlusion.Journal of surgical case reports · 2021Article
- Use of pCONUS HPC for the treatment of unruptured wide-necked bifurcation aneurysms: early clinical experience using single antiplatelet therapy.Stroke and vascular neurology · 2021Article
- Use of the pCONus HPC as an adjunct to coil occlusion of acutely ruptured aneurysms: early clinical experience using single antiplatelet therapy.Journal of neurointerventional surgery · 2020Article
- Complex Wide-necked and Lobulated Aneurysm of the Middle Cerebral Artery Bifurcation : Treatment with a pCONUS2 Neck Bridging Device and p48MW Flow Modulation Device.Clinical neuroradiology · 2020Article
- Advances in endovascular aneurysm management: coiling and adjunctive devices.Stroke and vascular neurology · 2020Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe authors sought to assess the safety and early efficacy of the pCONUS Bifurcation Aneurysm Implants in a meaningful number of patients; we performed a systematic review and meta-analysis for the treatment of 203 intracranial aneurysms.
methodsA literature search was performed by a reference librarian, and after screening nine case series were included in this analysis. We estimated from each study the cumulative incidence (event rate) and 95% confidence interval (CI) for each outcome. Event rates were pooled in a meta-analysis across studies using the random-effects model; descriptive statistics were reported when relevant.
resultsThe pCONUS devices can be used with a technical success rate of 100% (95% CI: 0.98-1.00) and a technical complication rate of 0% (95% CI: 0.00-0.02). Perioperative morbidity and mortality rates were 7% (95% CI: 0.03-0.11) and 0% (95% CI: 0.00-0.01), respectively. Perioperative hemorrhage rate was 0% (95% CI: 0.00-0.02); rate of treatment-related long-term neurological deficit was 2% (95% CI: 0.00-0.06). The long-term complete occlusion rate was 60% (95% CI: 0.52-0.69) and retreatment rate was 14% (95% CI: 0.06-0.22).
conclusionsThe pCONUS devices are an additional tool for the treatment of wide-necked intracranial aneurysms with high rates of technical success and sufficiently low rates of morbidity and mortality. Comparative studies with longer-term follow-up are needed to clarify the role of this device in the management of challenging aneurysms.
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