ArticleNPJ aging and mechanisms of disease2019
Tissue-specific alteration of gene expression and function by RU486 and the GeneSwitch system.
Article in NPJ aging and mechanisms of disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- UBA1 knockdown dysregulates UBA1-sensitive proteins and impairs muscle function in models of spinal muscular atrophy X-linked 2.Disease models & mechanisms · 2026Article
- Protocol for live-cell imaging of mitochondrial dynamics in adult Drosophila oenocytes.STAR protocols · 2026Article
- GSK-3β coordinates axonal microtubule organization through Shot and Tau.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
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- Perturbation of NAD(P)H metabolism with theScience advances · 2026Article
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- A carnitine transporter at the blood-brain barrier modulates sleep via glial lipid metabolism inProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Article
- Pharmacology of Aging:Aging biology · 2024Article
- The RU486-dependent activation of the GeneSwitch system in adult muscles leads to severe adverse effects in Drosophila.G3 (Bethesda, Md.) · 2024Article
- The importance of host physical niches for the stability of gut microbiome composition.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Review
- Article
- Time-restricted feeding promotes muscle function through purine cycle and AMPK signaling in Drosophila obesity models.Nature communications · 2023Article
- Modulation of protease expression by the transcription factor Ptx1/PITX regulates protein quality control during aging.Cell reports · 2023Article
- An optimized temporally controlled Gal4 system inFrontiers in neuroscience · 2023Article
- Azot expression in theCommunicative & integrative biology · 2023Article
- Drosophila melanogaster: a simple genetic model of kidney structure, function and disease.Nature reviews. Nephrology · 2022Review
- Muscle-to-Brain Signaling Via Myokines and Myometabolites.Brain plasticity (Amsterdam, Netherlands) · 2022Review
- Spatial control of gene expression in flies using bacterially derived binary transactivation systems.Insect molecular biology · 2021Article
- Activation of innate immunity during development induces unresolved dysbiotic inflammatory gut and shortens lifespan.Disease models & mechanisms · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
The GeneSwitch (GS) is a modified Gal4/UAS system, whereby transgene expression is induced in
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.