ArticleBiomicrofluidics2019
Experimental and numerical study of elasto-inertial focusing in straight channels.
Article in Biomicrofluidics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Computational methods for inertial microfluidics: recent advances and future perspectives.Microsystems & nanoengineering · 2025Review
- On-Chip Integration of Impedance Cytometry for Inline Optimization of Dielectrophoretic Separations on Multiple Cellular Biophysical Metrics.ACS sensors · 2025Article
- Neural Network-Enabled Multiparametric Impedance Signal Templating for High throughput Single-Cell Deformability Cytometry Under Viscoelastic Extensional Flows.Small (Weinheim an der Bergstrasse, Germany) · 2025Article
- Viscoelastic particle focusing and separation in a microfluidic channel with a cruciform section.Biomicrofluidics · 2024Article
- Elasto-inertial focusing and particle migration in high aspect ratio microchannels for high-throughput separation.Microsystems & nanoengineering · 2024Article
- Exploitation of elasto-inertial fluid flow for the separation of nano-sized particles: Simulating the isolation of extracellular vesicles.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2023Article
- Deciphering viscoelastic cell manipulation in rectangular microchannels.Physics of fluids (Woodbury, N.Y. : 1994) · 2023Article
- Particle Separation in a Microchannel with a T-Shaped Cross-Section Using Co-Flow of Newtonian and Viscoelastic Fluids.Micromachines · 2023Article
- A review on inertial microfluidic fabrication methods.Biomicrofluidics · 2023Review
- Sheathless inertial particle focusing methods within microfluidic devices: a review.Frontiers in bioengineering and biotechnology · 2023Review
- Elasto-Inertial Focusing Mechanisms of Particles in Shear-Thinning Viscoelastic Fluid in Rectangular Microchannels.Micromachines · 2022Article
- Particle Focusing in a Straight Microchannel with Non-Rectangular Cross-Section.Micromachines · 2022Article
- High throughput viscoelastic particle focusing and separation in spiral microchannels.Scientific reports · 2021Article
- Particle Focusing under Newtonian and Viscoelastic Flow in a Straight Rhombic Microchannel.Micromachines · 2020Article
- Universal motion of mirror-symmetric microparticles in confined Stokes flow.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Optimal Control of Colloidal Trajectories in Inertial Microfluidics Using the Saffman Effect.Micromachines · 2020Article
- The mechanical responses of advecting cells in confined flow.Biomicrofluidics · 2020Review
- 3D Printing of Inertial Microfluidic Devices.Scientific reports · 2020Article
- Influence of non-Newtonian power law rheology on inertial migration of particles in channel flow.Biomicrofluidics · 2020Article
- Viscoelastic microfluidics: progress and challenges.Microsystems & nanoengineering · 2020Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Elasto-inertial microfluidics has drawn significant attention in recent years due to its enhanced capabilities compared to pure inertial systems in control of small microparticles. Previous investigations have focused mainly on the applications of elasto-inertial sorting, rather than studying its fundamentals. This is because of the complexity of simulation and analysis, due to the presence of viscoelastic force. There have been some investigative efforts on the mechanisms of elasto-inertial focusing in straight channels; however, these studies were limited to simple rectangular channels and neglected the effects of geometry and flow rates on focusing positions. Herein, for the first time, we experimentally and numerically explore the effects of elasticity accompanying channel cross-sectional geometry and sample flow rates on the focusing phenomenon in elasto-inertial systems. The results reveal that increasing the aspect ratio weakens the elastic force more than inertial force, causing a transition from one focusing position to two. In addition, they show that increasing the angle of a channel corner causes the elastic force to push the particles more efficiently toward the center over a larger area of the channel cross section. Following on from this, we proposed a new complex straight channel which demonstrates a tighter focusing band compared to other channel geometries. Finally, we focused
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Registered trials
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