Efficacy of Artemisinin Base Combination Therapy and Genetic Diversity of

Jhons Fatriyadi Suwandi, Widya Asmara, Hari Kusnanto, Din Syafruddin, Supargiyono Supargiyono

Abstract read

In one paragraph

Article in Iranian journal of parasitology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it

0cells of the map it votes in

2citing papers in PubMed, 1 pooled it

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

Drug resistance of Plasmodium falciparum and Plasmodium vivax isolates in Indonesia.Malaria journal · 2022
Pooled it
Determinant of parasite clearance and density on uncomplicated falciparum malaria infections in malaria-endemic area of Lampung Province, Indonesia.Parasites, hosts and diseases · 2023
Observational

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jhons Fatriyadi SuwandiDepartment of Microbiology and Parasitology, Faculty of Medicine, University of Lampung, Bandar Lampung, Indonesia.

Widya AsmaraDepartment of Microbiology, Faculty of Veterinary Medicine, Gadjah Mada University, Jogjakarta, Indonesia.

Hari KusnantoDepartment of Public Health, Faculty of Medicine, Public Health and Nursing, Gadjah Mada University, Jogjakarta, Indonesia.

Din SyafruddinDepartment of Parasitology, Faculty of Medicine, Hasanuddin University, Makasar, Indonesia.

Supargiyono SupargiyonoDepartment of Parasitology, Faculty of Medicine, Public Health and Nursing, Gadjah Mada University, Jogjakarta, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMalaria is an infectious disease caused by

methodsThis study was observational analytic study of falciparum malaria patients treated with ACT and primaquine (DHP-PQ and AAQ-PQ) at Hanura Primary Health Centre (

resultsThe results of this research are DHP-PQ effectiveness was still wellness among falciparum malaria patients in District of Pesawaran, Province of Lampung, Indonesia. There is Single-nucleotide mutation of

conclusionTherapy of DHP-PQ as an antimalarial falciparum in Pesawaran District, Lampung, Indonesia is still good. The genetic variation found was the SNP on the N86Y PfMDR1 gene, with dominant allele MAD20 and 3D7.

Indexed as

Artemisinin combination therapyEfficacyGenetic variationPlasmodium falciparum

Identifiers

PMID31123479

PMCPMC6511592

What OpenQuestion holds

Textmetadata

LicenceCC BY

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.