Evidence map›Paper›PMID 31123390›Full record

ArticleJournal of the Royal Statistical Society. Series A, (Statistics in Society)2018

Bayesian joint modelling of longitudinal data on abstinence, frequency and intensity of drinking in alcoholism trials.

Eugenia Buta, Stephanie S O'Malley, Ralitza Gueorguieva

Abstract read
In one paragraph

Article in Journal of the Royal Statistical Society. Series A, (Statistics in Society), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Three-part random effect models for longitudinal skewed survey data with "not applicable" responses.Journal of educational and behavioral statistics : a quarterly publication sponsored by the American Educational Research Association and the American Statistical Association · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Eugenia ButaYale University, New Haven, USA.
Stephanie S O'MalleyYale University, New Haven, USA.
Ralitza GueorguievaYale University, New Haven, USA.

Funding

Translational Technologies CoreP50AA012870 · NIAAA · YALE UNIVERSITY · PI John H. Krystal · 2001 to 2026
$43.7M
Yale University Clinical and Translational Science Award ProgramUL1TR000142 · NCATS · YALE UNIVERSITY · PI SHERWIN, ROBERT S · 2012 to 2015
$31.8M
NCATS NIH HHS UL1 TR000142NIAAA NIH HHS P50 AA012870
6 · The paper itself

Abstract

In alcoholism research, several complementary outcomes are of interest:abstinence from drinking during a specific time frame, and, when the individual is drinking, frequency of drinking (the proportion of days on which drinking occurs) and intensity of drinking (the average number of drinks per drinking day). The outcomes are often measured repeatedly over time on the same subject and, although they are closely related, they are rarely modelled together. We propose a joint model that allows us to fit these longitudinal outcomes simultaneously, using correlated random effects to model the association between the outcomes and between repeated measurements on the same subject. The model has three parts: a logistic part for sustained abstinence over the period of interest, a truncated binomial part for frequency of drinking and a log-normal model for drinking intensity when drinking occurs. Because of the computational impracticality of fitting models with many random effects by using standard frequentist approaches, we use a Bayesian approach to fit the joint model. We also conduct a simulation study to investigate the gains in parameter estimate bias and mean-squared error associated with joint

Indexed as

Bayesian inferenceCorrelated random effectsDrinkingHurdle modelsJoint modellingZero inflation

Identifiers

PMID31123390
PMCPMC6527419

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.