SynthesisTranslational psychiatry2019
A genome-wide association meta-analysis of prognostic outcomes following cognitive behavioural therapy in individuals with anxiety and depressive disorders.
Abstract readMeta-Analysis
In one paragraph
Synthesis in Translational psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed.
- Prediction of Clinically Meaningful Improvement After Internet-Delivered Cognitive Behavioral Therapy for Depression and Anxiety Disorders: Machine Learning-Based Predictive Model Development and Temporal Validation Study.Journal of medical Internet research · 2026Article
- Cardiac vagal activity during in-vivo threat exposure is associated with within-session inhibition of fear and avoidance.Translational psychiatry · 2026Article
- Polygenic scores in the study of gene-environment interplay and stress-related psychopathology.Frontiers in psychiatry · 2026Review
- Differentially expressed transcripts associated with depressive symptoms during pregnancy and postpartum.Molecular psychiatry · 2025Article
- Association Between Polygenic Risk and Symptom Severity Change After Cognitive Behavioral Therapy for Obsessive-Compulsive Disorder.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2025Article
- Polygenic scores and symptom severity change after internet-delivered cognitive behaviour therapy for depression and anxiety.Discover mental health · 2025Article
- Research Review: A review of the past decade of family and genomic studies on adolescent mental health.Journal of child psychology and psychiatry, and allied disciplines · 2025Review
- Clinical, genetic, and sociodemographic predictors of symptom severity after internet-delivered cognitive behavioural therapy for depression and anxiety.BMC psychiatry · 2025Article
- Transcriptomics and psychotherapy: An integrative review.Brain, behavior, & immunity - health · 2024Review
- Rare and common variants associated with alcohol consumption identify a conserved molecular network.Alcohol, clinical & experimental research · 2024Article
- The genetic architecture of youth anxiety: a study protocol.BMC psychiatry · 2024Article
- Swedish multimodal cohort of patients with anxiety or depression treated with internet-delivered psychotherapy (MULTI-PSYCH).BMJ open · 2023Article
- Candidate biomarkers in psychiatric disorders: state of the field.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2023Article
- Psychotherapies and digital interventions for OCD in adults: What do we know, what do we need still to explore?Comprehensive psychiatry · 2023Review
- Predicting remission after internet-delivered psychotherapy in patients with depression using machine learning and multi-modal data.Translational psychiatry · 2022Article
- Symptom-level modelling unravels the shared genetic architecture of anxiety and depression.Nature human behaviour · 2021Article
- A bioinformatic study revealed serotonergic neurons are involved in the etiology and therapygenetics of anxiety disorders.Translational psychiatry · 2021Article
- The Cooperative Revolution Reaches Clinical Psychology and Psychotherapy: An Example From Germany.Clinical psychology in Europe · 2021Article
- Inclusion of genetic variants in an ensemble of gradient boosting decision trees does not improve the prediction of citalopram treatment response.Scientific reports · 2021Article
- Integrative DNA Methylation and Gene Expression Analysis of Cognitive Behavioral Therapy Response in Children and Adolescents with Obsessive-Compulsive Disorder; a Pilot Study.Pharmacogenomics and personalized medicine · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
54 authors.
Christopher RaynerSocial, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.ORCID http://orcid.org/0000-0003-2950-343X
Jonathan R I ColemanSocial, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.ORCID http://orcid.org/0000-0002-6759-0944
Kirstin L PurvesSocial, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.ORCID http://orcid.org/0000-0002-8110-5554
John HodsollBiostatistics and Health Informatics, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Kimberley GoldsmithBiostatistics and Health Informatics, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.ORCID http://orcid.org/0000-0002-0620-7868
Georg W AlpersDepartment of Psychology, School of Social Sciences, University of Mannheim, Mannheim, Germany.
Evelyn AnderssonCentre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Volker AroltDepartment of Psychiatry and Psychotherapy, University of Münster, Münster, Germany.
Julia BobergCentre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Susan BögelsResearch Institute Child Development and Education, University of Amsterdam, Amsterdam, The Netherlands.
Cathy CreswellSchool of Psychology and Clinical Language Sciences, University of Reading, Reading, UK.
Peter CooperSchool of Psychology and Clinical Language Sciences, University of Reading, Reading, UK.
Charles CurtisSocial, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Jürgen DeckertDepartment of Psychiatry, Psychosomatic Medicine and Psychotherapy, University of Würzburg, Würzburg, 97078, Germany.
Katharina DomschkeFaculty of Medicine, Department of Psychiatry and Psychotherapy, Medical Center, University of Freiburg, Freiburg, Germany.
Samir El AlaouiCentre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.ORCID http://orcid.org/0000-0002-6590-1606
Lydia FehmDepartment of Psychology, Humboldt-Universität zu Berlin, Berlin, Germany.
Thomas FydrichDepartment of Psychology, Humboldt-Universität zu Berlin, Berlin, Germany.
Alexander L GerlachClinical Psychology and Psychotherapy, University of Cologne, Cologne, Germany.ORCID http://orcid.org/0000-0001-6794-5349
Anja GrocholewskiDepartment of Psychology, University of Braunschweig, Braunschweig, Germany.
Kurt HahlwegDepartment of Psychology, University of Braunschweig, Braunschweig, Germany.
Alfons HammDepartment of Biological and Clinical Psychology, University of Greifswald, Greifswald, Germany.
Erik HedmanCentre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Einar R HeiervangDivision of Mental Health and Addiction, Department of Child and Adolescent Psychiatry, Oslo University Hospital, Oslo, Norway.
Jennifer L HudsonCentre for Emotional Health, Department of Psychology, Macquarie University, Sydney, Australia.
Peter JöhrenMental Health Research and Treatment Center, Ruhr-Universität Bochum, Bochum, Germany.
Robert KeersDepartment of Biological and Experimental Psychology, School of Biological and Chemical Sciences, Queen Mary University of London, London, UK.
Tilo KircherDepartment of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany.
Thomas LangChristoph-Dornier-Stiftung für Klinische Psychologie, Institut für Klinische Psychologie und Psychotherapie, Bremen, Germany.
Catharina LavebrattNeurogenetics Unit, Center for Molecular Medicine, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.ORCID http://orcid.org/0000-0003-4987-2718
Sang-Hyuck LeeSocial, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Kathryn J LesterSocial, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Nils LindeforsCentre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Jürgen MargrafMental Health Research and Treatment Center, Ruhr-Universität Bochum, Bochum, Germany.
Maaike NautaDepartment of Clinical Psychology and Experimental Psychopathology, University of Groningen, Groningen, The Netherlands.
Christiane A Pané-FarréDepartment of Biological and Clinical Psychology, University of Greifswald, Greifswald, Germany.
Paul PauliDepartment of Psychology (Biological Psychology, Clinical Psychology, and Psychotherapy), University of Würzburg, Würzburg, Germany.ORCID http://orcid.org/0000-0003-0692-6720
Ronald M RapeeCentre for Emotional Health, Department of Psychology, Macquarie University, Sydney, Australia.
Andreas ReifDepartment of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Frankfurt am Main, Germany.
Winfried RiefDepartment of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany.
Susanna RobertsDepartment of Psychology, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Martin SchallingNeurogenetics Unit, Center for Molecular Medicine, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
Silvia SchneiderMental Health Research and Treatment Center, Ruhr-Universität Bochum, Bochum, Germany.
Wendy K SilvermanChild Study Center, Yale University School of Medicine, New Haven, CT, USA.
Andreas StröhleDepartment of Psychiatry and Psychotherapy, Campus Charité Mitte, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Tobias TeismannMental Health Research and Treatment Center, Ruhr-Universität Bochum, Bochum, Germany.
Mikael ThastumDepartment of Psychology and Behavioural Sciences, Aarhus University, Aarhus, Denmark.
Andre WannemüllerMental Health Research and Treatment Center, Ruhr-Universität Bochum, Bochum, Germany.
Heike WeberDepartment of Psychiatry, Psychosomatic Medicine and Psychotherapy, University of Würzburg, Würzburg, 97078, Germany.ORCID http://orcid.org/0000-0002-9421-1292
Hans-Ulrich WittchenInstitute of Clinical Psychology and Psychotherapy, Technische Universität Dresden, Dresden, Germany.
Christiane WolfDepartment of Psychiatry, Psychosomatic Medicine and Psychotherapy, University of Würzburg, Würzburg, 97078, Germany.
Christian RückCentre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.ORCID http://orcid.org/0000-0002-8742-0168
Gerome BreenSocial, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK. gerome.breen@kcl.ac.uk.ORCID http://orcid.org/0000-0003-2053-1792
Thalia C EleySocial, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK. thalia.eley@kcl.ac.uk.ORCID http://orcid.org/0000-0001-6458-0700
Funding
Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9MParent Mediation of Child Anxiety CBT OutcomeR01MH079943 · NIMH · FLORIDA INTERNATIONAL UNIVERSITY · PI PETTIT, JEREMY W · 2008 to 2012
$3.0MDepartment of Health PB-PG-0107-12042Department of Health RP_2014-04-018Medical Research Council G0601020Medical Research Council G0601874Medical Research Council G0802326Medical Research Council MR/K021281/1Medical Research Council MR/K021281/2Medical Research Council MR/M021475/1NCATS NIH HHS UL1 TR001863NIMH NIH HHS R01 MH079943
Abstract
Major depressive disorder and the anxiety disorders are highly prevalent, disabling and moderately heritable. Depression and anxiety are also highly comorbid and have a strong genetic correlation (r
Indexed as
AdultAnxiety DisordersChildCognitive Behavioral TherapyGenome-Wide Association StudyHumansMajor Depressive DisorderOutcome Assessment, Health Care
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