ArticleScientific reports2019
Vaginal Microbiota Composition Correlates Between Pap Smear Microscopy and Next Generation Sequencing and Associates to Socioeconomic Status.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- The Association Between Vaginal Microbiota Dysbiosis, Bacterial Vaginosis, and Aerobic Vaginitis, and Adverse Pregnancy Outcomes of Women Living in Sub-Saharan Africa: A Systematic Review.Frontiers in public health · 2020Pooled it
- Vaginal microbiota impacts of a Lactobacillus crispatus live biotherapeutic and predictors of colonization in randomized controlled trial.Cell host & microbe · 2026Trial
- Vaginal microbiomes and their pertinent social context: a microbial ecological review proffering AMR-STI acquisition and emergence.Biology of sex differences · 2026Review
- Exploratory analyses of cervicovaginal mucus O-glycan composition and microbiota profiles in unexplained infertility.Glycobiology · 2026Article
- Bacterial vaginosis in microscopic examination of Pap smears in patients with high-risk HPV is associated with viral persistence and cytological progression in a longitudinal study.Infectious agents and cancer · 2026Article
- Population-level analyses identify host and environmental variables influencing the vaginal microbiome.Signal transduction and targeted therapy · 2025Article
- Article
- Citizen science as an instrument for women's health research.Nature medicine · 2024Article
- Viewing Native American Cervical Cancer Disparities through the Lens of the Vaginal Microbiome: A Pilot Study.Cancer prevention research (Philadelphia, Pa.) · 2024Article
- Exploring Oral and Vaginal Probiotic Solutions for Women's Health from Puberty to Menopause: A Narrative Review.Microorganisms · 2024Review
- Untangling Associations of Microbiomes of Pregnancy and Preterm Birth.Clinics in perinatology · 2024Review
- Host factors are associated with vaginal microbiome structure in pregnancy in the ECHO Cohort Consortium.Scientific reports · 2024Article
- Changes in the Vaginal Microbiome During Pregnancy and the Postpartum Period in South African Women: a Longitudinal Study.Reproductive sciences (Thousand Oaks, Calif.) · 2024Article
- Economic microbiology: exploring microbes as agents in economic systems.Frontiers in microbiology · 2024Review
- Longitudinal analysis of vaginal microbiota during IVF fresh embryo transfer and in early pregnancy.Microbiology spectrum · 2023Article
- Joint effects of individual socioeconomic status and residential neighborhood context on vaginal microbiome composition.Frontiers in public health · 2023Article
- Transplantation of maternal intestinal flora to the newborn after elective cesarean section (SECFLOR): study protocol for a double blinded randomized controlled trial.BMC pediatrics · 2022Article
- Parity and gestational age are associated with vaginal microbiota composition in term and late term pregnancies.EBioMedicine · 2022Article
- Vaginal Secretion Epithelium Count as a Prognostic Indicator of High Abundance of Ureaplasmas in Women with a Normal Nugent Score.Polish journal of microbiology · 2022Article
- Cervicovaginal Complement Activation and Microbiota During Pregnancy and in Parturition.Frontiers in immunology · 2022Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent research on vaginal microbiota relies on high throughput sequencing while microscopic methods have a long history in clinical use. We investigated the correspondence between microscopic findings of Pap smears and the vaginal microbiota composition determined by next generation sequencing among 50 asymptomatic women. Both methods produced coherent results regarding the distinction between Lactobacillus-dominant versus mixed microbiota, reassuring gynaecologists for the use of Pap smear or wet mount microscopy for rapid evaluation of vaginal bacteria as part of diagnosis. Cytologic findings identified women with bacterial vaginosis and revealed that cytolysis of vaginal epithelial cells is associated to Lactobacillus crispatus-dominated microbiota. Education and socio-economic status were associated to the vaginal microbiota variation. Our results highlight the importance of including socio-economic status as a co-factor in future vaginal microbiota studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.