ArticleProceedings of the National Academy of Sciences of the United States of America2019
Implantable multireservoir device with stimulus-responsive membrane for on-demand and pulsatile delivery of growth hormone.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 35 citations in OpenAlex.
- A gastric retentive robotic capsule enables emergency-prepared and responsive oral drug delivery in canine models.Science advances · 2025Article
- Novel perspectives on growth hormone regulation of ovarian function: mechanisms, formulations, and therapeutic applications.Frontiers in endocrinology · 2025Review
- Implantable device actuated by manual button clicks for noninvasive self-drug administration.Bioengineering & translational medicine · 2023Article
- Construction and Biological Evaluation of Multiple Modification Hollow Mesoporous Silicone Doxorubicin Nanodrug Delivery System.AAPS PharmSciTech · 2022Article
- Microelectromechanical Systems (MEMS) for Biomedical Applications.Micromachines · 2022Review
- Photomechanical Polymer Nanocomposites for Drug Delivery Devices.Molecules (Basel, Switzerland) · 2021Article
- Silicon Nanofluidic Membrane for Electrostatic Control of Drugs and Analytes Elution.Pharmaceutics · 2020Article
- Electrostatically gated nanofluidic membrane for ultra-low power controlled drug delivery.Lab on a chip · 2020Article
- Recent Advances in Micro-Electro-Mechanical Devices for Controlled Drug Release Applications.Frontiers in bioengineering and biotechnology · 2020Review
Corrections and comments
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Authors and funding
13 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Implantable devices for on-demand and pulsatile drug delivery have attracted considerable attention; however, many devices in clinical use are embedded with the electronic units and battery inside, hence making them large and heavy for implantation. Therefore, we propose an implantable device with multiple drug reservoirs capped with a stimulus-responsive membrane (SRM) for on-demand and pulsatile drug delivery. The SRM is made of thermosensitive POSS(MEO
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.