Evidence map›Paper›PMID 31123077›Full record

ArticleOccupational and environmental medicine2019

Occupational exposure to organic particles and combustion products during pregnancy and birth outcome in a nationwide cohort study in Sweden.

Filip Norlén, Per Gustavsson, Pernilla Wiebert, Lars Rylander, Magnus Westgren, Nils Plato, Maria Albin, Jenny Selander

Abstract read
In one paragraph

Article in Occupational and environmental medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Filip NorlénInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0001-9012-3378
Per GustavssonInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0003-2221-8599
Pernilla WiebertInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Lars RylanderDivision of Occupational and Environmental Medicine, Lund University, Lund, Sweden.
Magnus WestgrenDepartment of Clinical Science, Intervention and Technology, Karolinska Universitetssjukhuset, Stockholm, Sweden.
Nils PlatoInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Maria AlbinInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Jenny SelanderInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo study if children of women exposed to organic particles and combustion products at work during pregnancy, have an increased risk of low birth weight, preterm birth or small for gestational age.

methodsA nationwide cohort of all occupationally active mothers and their children from single births during 1994 to the end of 2012 (1 182 138 observations) was formed. Information on birth outcome was obtained from the medical birth register. Information on absence from work, education, occupation, age, nationality and smoking habits was obtained from national registers. A job exposure matrix (FINJEM) was used to assess the exposure.

resultsPregnant women with low absence from work and high (>50th percentile) exposure to organic particles had an increased risk of giving birth to children with low birth weight (OR=1.19; 95% CI: 1.07 to 1.32), small for gestational age (OR=1.22; 95% CI: 1.07 to 1.38) or preterm birth (OR=1.17; 95% CI: 1.08 to 1.27). Subgroup analyses showed an increased risk of small for gestational age in association with exposure to oil mist. Exposure to oil mist and cooking fumes was associated with low birth weight. Paper and other organic dust was associated with preterm birth. Exposure to combustion products showed an increased risk of small for gestational age (OR=1.40; 95% CI: 1.15 to 1.71).

conclusionsThe results indicate that occupational exposure to organic particles or combustion products during pregnancy is associated with restriction of fetal growth and preterm birth. More studies are needed to confirm a casual association.

Indexed as

Infant, Low Birth WeightInfant, Small for Gestational AgeAdultAir Pollutants, OccupationalCohort StudiesCookingFemaleHumansInfant, NewbornMaternal ExposureOccupational ExposureOilsParticulate MatterPolycyclic Aromatic HydrocarbonsPregnancyPremature BirthAir Pollutants, OccupationalOilsParticulate MatterPolycyclic Aromatic Hydrocarbonsepidemiologyfemale reproductive effects and adverse pregnancy outcomesorganic dusts

Identifiers

PMID31123077
PMCPMC6703147

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.