Evidence map›Paper›PMID 31123052›Full record

ReviewClinical cancer research : an official journal of the American Association for Cancer Research2019

Pathogen Molecular Pattern Receptor Agonists: Treating Cancer by Mimicking Infection.

Mark Aleynick, Judit Svensson-Arvelund, Christopher R Flowers, Aurélien Marabelle, Joshua D Brody

Abstract readReview
In one paragraph

Review in Clinical cancer research : an official journal of the American Association for Cancer Research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Human anthrax vaccines: Current status and future prospects.Human vaccines & immunotherapeutics · 2025
    Review
  6. Review
  7. Polio virotherapy provokes MDA5 signaling and CD4Microbiology and molecular biology reviews : MMBR · 2025
    Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Exploring treatment options in cancer: Tumor treatment strategies.Signal transduction and targeted therapy · 2024
    Review
  14. Article
  15. Article
  16. Vaccine adjuvants: mechanisms and platforms.Signal transduction and targeted therapy · 2023
    Review
  17. Article
  18. Article
  19. 4-1BB and cytokines trigger human NK, γδ T, and CD8Immunity, inflammation and disease · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mark AleynickPrecision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York.ORCID 0000-0001-6113-4182
Judit Svensson-ArvelundPrecision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York.ORCID 0000-0002-6260-0808
Christopher R FlowersWinship Cancer Institute of Emory University, Emory University School of Medicine, Atlanta, Georgia.
Aurélien MarabelleCancer Immunotherapy Program, Gustave Roussy, Villejuif, France.ORCID 0000-0002-5816-3019
Joshua D BrodyPrecision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York. joshua.brody@mssm.edu.

Funding

Potentiating Checkpoint Blockade by Cross-Priming Tumor-Reactive T cells with In Situ VaccinationR37CA246239 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Joshua D Brody · 2020 to 2026
$2.6M
NCI NIH HHS R37 CA246239
6 · The paper itself

Abstract

Immunotherapies such as checkpoint blockade have achieved durable benefits for patients with advanced stage cancer and have changed treatment paradigms. However, these therapies rely on a patient's own

Indexed as

ImmunotherapyAntigen-Presenting CellsAntigens, NeoplasmCell Cycle CheckpointsHumansInflammationNeoplasmsNeoplasm StagingReceptors, Pattern RecognitionT-LymphocytesTumor MicroenvironmentAntigens, NeoplasmReceptors, Pattern Recognition

Identifiers

PMID31123052
PMCPMC11734666

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.