Evidence map›Paper›PMID 31122997›Full record

ArticleBMJ open2019

'Reducing Delays In Vaccination' (REDIVAC) trial: a protocol for a randomised controlled trial of a web-based, individually tailored, educational intervention to improve timeliness of infant vaccination.

Amanda F Dempsey, Nicole Wagner, Komal Narwaney, Jennifer Pyrzanowski, Bethany M Kwan, Courtney Kraus, Kathy Gleason, Ken Resnicow, Carter Sevick, Jessica Cataldi and 2 more

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02665013 (Reducing Delay of Vaccination in Children Study), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02665013 nacompletednot on this map

Reducing Delay of Vaccination in Children Study

TypeinterventionalSponsorKaiser PermanenteRan2016 to 2019Enrolled824ConditionsCommunicable DiseasesArmsTailored, Untailored
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Amanda F DempseyDepartment of Pediatrics, University of Colorado Denver, Denver, Colorado, USA.
Nicole WagnerInstitute for Health Research, Kaiser Permanente Colorado, Denver, Colorado, USA.
Komal NarwaneyInstitute for Health Research, Kaiser Permanente Colorado, Denver, Colorado, USA.
Jennifer PyrzanowskiDepartment of Pediatrics, University of Colorado Denver, Denver, Colorado, USA.
Bethany M KwanDepartment of Family Medicine, University of Colorado School of Medicine, Aurora, Colorado, USA.ORCID 0000-0002-4013-5618
Courtney KrausInstitute for Health Research, Kaiser Permanente, Denver, Colorado, USA.
Kathy GleasonInstitute for Health Research, Kaiser Permanente Colorado, Denver, Colorado, USA.
Ken ResnicowHealth Education and Health Behavior, University of Michigan, Ann Arbor, Michigan, USA.
Carter SevickDepartment of Pediatrics, University of Colorado Denver, Denver, Colorado, USA.
Jessica CataldiDepartment of Pediatrics, University of Colorado Denver, Denver, Colorado, USA.
Sarah E BrewerDepartment of Pediatrics, University of Colorado Denver, Denver, Colorado, USA.
Jason M GlanzInstitute for Health Research, Kaiser Permanente Colorado, Denver, Colorado, USA.
University of Colorado Denver · USKaiser Permanente · USUniversity of Michigan · US

Funding

The REDIVAC Study - Reducing Delay In Vaccination of Children StudyR01HD079457 · NICHD · UNIVERSITY OF COLORADO DENVER · PI DEMPSEY, AMANDA F, GLANZ, JASON M · 2014 to 2018
$2.6M
NICHD NIH HHS R01 HD079457
6 · The paper itself

Abstract

introductionIncreasing numbers of children are failing to receive many recommended vaccines, which has led to significant outbreaks of vaccine-preventable diseases in the USA and worldwide. A major driver of undervaccination is parental vaccine hesitance. Prior research demonstrates that mothers are the primary decision maker for infant vaccination, and that their vaccination attitudes form primarily during pregnancy and early in their infant's life. METHODS AND ANALYSIS: This manuscript describes the protocol for an ongoing three-armed randomised controlled trial done at Kaiser Permanente Colorado (KPCO). The trial aims to test the efficacy of provided tailored, individualised information via the Internet to pregnant and new mothers versus untailored information versus usual care on the timeliness of infant vaccination. The primary outcome to be assessed is vaccination status, which is a dichotomous outcome (up to date vs not) assessed at age 200 days, reflecting the time when infants should have completed the first set of vaccine provided (at age 2, 4 and 6 months). Infants with one or more age-appropriate recommended vaccines at least 30 days delayed are categorised as not up to date whereas all other infants are considered up to date. Secondary outcomes include vaccination status at age 489 days, reflecting receipt of recommended vaccines at age 12-15 months, as well as vaccination attitudes, hesitancy and intention. Vaccination data will be derived from the electronic medical record and the state immunisation registry. Other secondary outcomes will be assessed by online surveys. ETHICS AND DISSEMINATION: The study activities were approved by the Institutional Review Boards of the University of Colorado, KPCO and the University of Michigan. Results will be disseminated through peer-reviewed manuscripts and conference presentations. TRIAL REGISTRATION NUMBER: NCT02665013; Pre-results.

Indexed as

Immunization SchedulePatient ComplianceAttitude to HealthFemaleHealth BehaviorHumansInfantInternet-Based InterventionMothersPatient Education as TopicRandomized Controlled Trials as TopicVaccination Refusalimmunisationmothersrandomised controlled trialvaccine hesitancy

Identifiers

PMID31122997
PMCPMC6538084
OpenAlexW2945142767

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.