ArticleBMJ open2019
Association between homocysteine, vitamin B
Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Association between serum homocysteine and erectile dysfunction: a systematic review and meta-analysis.International journal of impotence research · 2025Pooled it
- Unraveling the Causal Association Between Circulating Copper Levels and Erectile Dysfunction: A Comprehensive Analysis via Bidirectional Two Sample Mendelian Randomization Study.Food science & nutrition · 2025Article
- Dietary intakes of vitamin BTranslational andrology and urology · 2024Article
- Article
- Homocysteine levels correlate with AVSS-RigiScan test parameters in men with erectile dysfunction.Basic and clinical andrology · 2023Article
- Is Arabic Information on YouTube About Erectile Dysfunction Based on Scientific Evidence?Research and reports in urology · 2023Article
- Serum folic acid: an effective indicator for arteriogenic erectile dysfunction.Frontiers in endocrinology · 2023Article
- Homocysteine levels correlate with velocimetric parameters in patients with erectile dysfunction undergoing penile duplex ultrasound.Andrology · 2022Article
- Significance of hyperhomocysteinaemia as an effective marker for vasculogenic erectile dysfunction: a cross-sectional study.Translational andrology and urology · 2022Article
- Serum Folic Acid and Erectile Dysfunction: A Systematic Review and Meta-Analysis.Sexual medicine · 2021Review
- Hyperhomocysteinemia: Focus on Endothelial Damage as a Cause of Erectile Dysfunction.International journal of molecular sciences · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesErectile dysfunction (ED) affects up to 53.4% of men aged 30-80 years. In this study, we aimed to examine the association between homocysteine (HCY), vitamin B
designCross-sectional study.
settingGuangxi, China.
participantsA total of 1381 participants who completed questionnaires were included, between September 2009 and December 2009. MEASURES: ED was evaluated by the International Index of Erectile Function scores. Also, the values of HCY, B12 and FA were acquired. Then, regression and between-group analyses were performed.
resultsNo association between FA and ED was found. Significant correlations between HCY and ED were found-the relationships between these two parameters were most notable in men aged over 60 years and in men living alone (bachelors or bachelorhood). B12 levels were higher in men with ED (718.53±234.37 pg/mL vs 688.74±229.68, p=0.015). Using multinomial logistic regression analyses, B12 levels were related to mild ED (multivariate adjusted analysis: OR 1.620, 95% CI 1.141 to 2.300, p=0.007), especially among men aged 40-49 years (OR 2.907, 95% CI 1.402 to 6.026, p=0.004).
conclusionsWe report, for the first time, a relationship between B12 levels and ED. We also found specific cohorts of men for whom the relationship between HCY levels and ED is most prominent. Further studies are required to elucidate the mechanisms underlying these relationships-these may ultimately result in new therapies for ED.
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Registered trials
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