ArticleBMJ case reports2019
False-positive troponin I elevation in a newborn with neonatal encephalopathy.
Article in BMJ case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 6 citations in OpenAlex.
- Case report: False-positive B-type natriuretic peptide results with the cyclic amplified fluorescence immunoassay.The Journal of international medical research · 2025Article
- Unexpected high troponin T and I values in a child with hypertrophic cardiomyopathy and acute chest pain: a case report.European heart journal. Case reports · 2023Article
- Predictive value of cord blood myocardial enzyme and troponin levels for myocardial injury after neonatal asphyxia.American journal of translational research · 2023Article
- Characterization of canine anti-mouse antibodies highlights that multiple strategies are needed to combat immunoassay interference.Scientific reports · 2019Article
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Serum biomarkers of myocardial damage are commonly used in babies after perinatal asphyxia. We present a case report of a persistently troponin I elevation without evidence of clinical or instrumental signs of myocardial ischaemia in a baby with perinatal asphyxia. When the blood was mixed with polyethylene glycol we found that the troponin I levels were falsely elevated due to interfering antibodies. This case shows that analytical errors may still occur despite modern immunoassay systems and underlines the need for further investigations to identify false-positive values in case of disagreement between clinical conditions and laboratory values.
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