Evidence map›Paper›PMID 31122910›Full record

ArticleBlood advances2019

Gilteritinib induces differentiation in relapsed and refractory

Christine M McMahon, Jonathan Canaani, Bryan Rea, Rachel L Sargent, Julianne N Qualtieri, Christopher D Watt, Jennifer J D Morrissette, Martin Carroll, Alexander E Perl

Abstract read
In one paragraph

Article in Blood advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed.

  1. Trial
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  13. Targeting WNK1 Releases Differentiation Block in Acute Myeloid Leukemia.bioRxiv : the preprint server for biology · 2026
    Article
  14. Article
  15. Review
  16. Review
  17. Review
  18. Review
  19. RNA activation ofMolecular therapy. Nucleic acids · 2025
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Christine M McMahonDivision of Hematology and Oncology, University of Pennsylvania, Philadelphia, PA.ORCID 0000-0001-9745-9595
Jonathan CanaaniHematology Division, Chaim Sheba Medical Center, Tel Aviv University, Tel-Hashomer, Israel.
Bryan ReaDepartment of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA.
Rachel L SargentJanssen Research and Development, Spring House, PA.ORCID 0000-0002-1420-0113
Julianne N QualtieriDepartment of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA; and.
Christopher D WattDepartment of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA; and.
Jennifer J D MorrissetteDepartment of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA; and.
Martin CarrollDivision of Hematology and Oncology, University of Pennsylvania, Philadelphia, PA.
Alexander E PerlDivision of Hematology and Oncology, University of Pennsylvania, Philadelphia, PA.ORCID 0000-0002-1463-2231

Funding

NRSA Training CoreTL1TR001880 · NCATS · UNIVERSITY OF PENNSYLVANIA · PI MEAGHER, EMMA ANNE · 2016 to 2025
$10.0M
Understanding and Targeting Chemotherapy Resistance in Acute Myeloid LeukemiaR01CA198089 · NCI · UNIVERSITY OF PENNSYLVANIA · PI CARROLL, MARTIN · 2015 to 2019
$3.3M
How Does FLT3 Mutation Regulate Myeloid Differentiation in Acute Myeloid LeukemiaR21CA198621 · NCI · UNIVERSITY OF PENNSYLVANIA · PI CARROLL, MARTIN · 2015 to 2016
$396k
NCATS NIH HHS TL1 TR001880NCI NIH HHS R01 CA198089NCI NIH HHS R21 CA198621
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Aniline CompoundsCell Differentiationfms-Like Tyrosine Kinase 3HumansLeukemia, Myeloid, AcutePyrazinesRecurrenceAniline CompoundsFLT3 protein, humanfms-Like Tyrosine Kinase 3gilteritinibPyrazines

Identifiers

PMID31122910
PMCPMC6538870

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.