ArticleUltrasound in medicine & biology2019
An Ultrasound Vibro-Elastography Technique for Assessing Papilledema.
Article in Ultrasound in medicine & biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 23 citations in OpenAlex.
- Increased optic nerve stiffness can aid in localizing ipsilateral brain or eye lesions in patients with secondary headaches.Quantitative imaging in medicine and surgery · 2025Article
- A noninvasive ultrasound vibro-elastography technique for assessing ocular lesions.Ultrasonics · 2025Article
- Mathematical Models for Ultrasound Elastography: Recent Advances to Improve Accuracy and Clinical Utility.Bioengineering (Basel, Switzerland) · 2024Review
- Quantitative Optical Coherence Elastography of the Optic Nerve Head In Vivo.IEEE transactions on bio-medical engineering · 2024Article
- Non-invasive Measurement of the Viscoelasticity of the Optic Nerve and Sclera for Assessing Papilledema: A Pilot Clinical Study.Ultrasound in medicine & biology · 2023Article
- Simultaneous Assessment of the Whole Eye Biomechanics Using Ultrasonic Elastography.IEEE transactions on bio-medical engineering · 2023Article
- High-Frequency Ultrasound Elastography to Assess the Nonlinear Elastic Properties of the Cornea and Ciliary Body.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2022Article
- High resolution optical coherence elastography of retina under prosthetic electrode.Quantitative imaging in medicine and surgery · 2021Article
- Ultrasonic elastography to assess biomechanical properties of the optic nerve head and peripapillary sclera of the eye.Ultrasonics · 2021Article
- Article
- Pathogenesis and Evaluation of the Effects of Idiopathic Intracranial Hypertension on the Optic Nerves.Neuro-ophthalmology (Aeolus Press) · 2020Review
- Low-frequency HIFU induced cancer immunotherapy: tempting challenges and potential opportunities.Cancer biology & medicine · 2019Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Papilledemais optic nerve swelling caused by increased intracranial hypertension, which has the potential to cause significant vision loss. Papilledema from idiopathic intracranial hypertension (IIH) is typically bilateral and symmetric, but can be asymmetric and even unilateral. The purpose of this study was to develop ultrasound vibro-elastography (UVE) for non-invasive measurement of ocular tissue wave speed for patients with papilledema. A total of 9 patients with papilledema from IIH and 9 age-matched healthy control patients were enrolled in this study. A local, gentle, 0.1-s harmonic vibration was applied on the eyelid to generate wave propagation in the ocular tissue. We used 3 excitation frequencies of 100, 150 and 200 Hz to measure the wave speeds. A 6.4-MHz ultrasound probe was used to non-invasively measure wave propagation in the ocular structures. Wave speeds were analyzed in the posterior sclera of the maculae of the eyes. The magnitudes of wave speed at each frequency of the IIH patients' posterior sclera were significantly higher than those of healthy patients. It was found that the magnitudes of wave speed at each frequency were statistically higher in the eyes with papilledema than in the contralateral eyes without papilledema for the patients with unilateral papilledema. UVE provides a non-invasive technique to measure the wave speed of posterior sclera, which may be useful for assessing patients with papilledema.
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