ArticleAutonomic neuroscience : basic & clinical2019
Sex and gender influence symptom manifestation and survival in multiple system atrophy.
Article in Autonomic neuroscience : basic & clinical, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Sex differences in alpha-synucleinopathies: a systematic review.Frontiers in neurology · 2023Pooled it
- Chromosome X-wide association study in multiple system atrophy identifies sex-differential risk loci.Brain : a journal of neurology · 2026Article
- Different brain spatial metabolic patterns characterizing different subtypes of multiple system atrophy.Journal of Parkinson's disease · 2026Article
- Sex-Dependent Effects of CSF1R-Mediated Myeloid Cell Depletion in a Mouse Model of Multiple System Atrophy.The European journal of neuroscience · 2026Article
- Drug repurposing for disease-modifying effects in multiple system atrophy.Translational neurodegeneration · 2026Review
- Speech impairment in a large sample of patients with multiple system atrophy: effect of gender and language.Journal of neural transmission (Vienna, Austria : 1996) · 2026Article
- Female mice exhibit resistance to disease progression despite early pathology in a transgenic mouse model inoculated with alpha-synuclein fibrils.Communications biology · 2025Article
- Epidemiologic and clinical features of multisystem atrophy: a population-based study in Navarre, Spain.Journal of neurology · 2024Observational
- Sex-related differences in the clinical presentation of multiple system atrophy.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2024Review
- In vivo cerebral metabolic and dopaminergic characteristics in multiple system atrophy with orthostatic hypotension.European journal of nuclear medicine and molecular imaging · 2024Article
- Development and Validation of a Prognostic Model to Predict Overall Survival in Multiple System Atrophy.Movement disorders clinical practice · 2023Article
- Sex and Gender Influence Urinary Symptoms and Management in Multiple System Atrophy.Journal of movement disorders · 2023Article
- The Effects of Deep Brain Stimulation in Patients with Multiple System Atrophy.Journal of Parkinson's disease · 2022Article
- Age and Gender Differences in Cardiovascular Autonomic Failure in the Transgenic PLP-syn Mouse, a Model of Multiple System Atrophy.Frontiers in neurology · 2022Article
- Lower Vitamin B12 Level at Multiple System Atrophy Diagnosis Is Associated With Shorter Survival.Movement disorders : official journal of the Movement Disorder Society · 2020Article
- Effects of gender on cognitive and behavioral manifestations in multiple system atrophy.Journal of neural transmission (Vienna, Austria : 1996) · 2020Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
Abstract
To evaluate the influence of sex and gender on clinical characteristics and survival in multiple system atrophy (MSA), we reviewed MSA patients with autonomic testing 1998-2012. Of 685 patients, 52% were male. Median survival overall was 7.3 years for males, 7.6 years for females. Survival from diagnosis was 2.9 years in males, 3.8 years in females. Females were more likely to initially manifest motor symptoms. Males were more likely to have orthostatic intolerance and early catheterization. In conclusion, our data show longer survival from diagnosis in females and slight overall survival benefit which may be related to initial motor manifestations.
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Registered trials
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