Evidence map›Paper›PMID 31122507›Full record

ArticleThe Journal of adolescent health : official publication of the Society for Adolescent Medicine2019

Adolescents' E-Cigarette Use: Increases in Frequency, Dependence, and Nicotine Exposure Over 12 Months.

Erin A Vogel, Judith J Prochaska, Danielle E Ramo, Jerome Andres, Mark L Rubinstein

Registry-linked trialAbstract read
In one paragraph

Article in The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07009509 (Pilot and Feasibility Testing of a Peer-led Program to Prevent Youth Nicotine Vaping), which is not on this map. Cited by 66 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07009509 narecruitingnot on this mapstarted 2024, after this paper: background citation

Pilot and Feasibility Testing of a Peer-led Program to Prevent Youth Nicotine Vaping: The YES-CAN! Program

TypeinterventionalSponsorUniversity of Colorado, DenverRan2024 to 2026Enrolled1,166ConditionsNicotine VapingArmsYES-CAN! program
3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. The Use of Machine Learning to Predict Offline Adolescent e-Cigarette Use: a Proof-of-Concept.Prevention science : the official journal of the Society for Prevention Research · 2026
    Article
  6. Factors Associated With Victorian Adolescents' Harm Perceptions and Attitudes About e-Cigarettes.Health promotion journal of Australia : official journal of Australian Association of Health Promotion Professionals · 2026
    Article
  7. Measurement invariance in the Youth Electronic Cigarette Outcome Expectancies Questionnaire across sex and race/ethnicity in pre- to early adolescence.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2026
    Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Social Media Engagement and Quit Intentions Among Youth With Exclusive E-cigarette Use: The Moderating Role of Social Norms.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025
    Article
  17. Trends and Sociodemographic Differences in Tobacco/Nicotine Transitions Among U.S. Adolescents and Young Adults Using e-cigarettes, 2014-2023.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2025
    Article
  18. Article
  19. Observational
  20. Article

6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Erin A VogelDepartment of Psychiatry and Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, California.
Judith J ProchaskaStanford Prevention Research Center, Department of Medicine, Stanford University, Stanford, California.
Danielle E RamoDepartment of Psychiatry and Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, California.
Jerome AndresUniversity of California, Berkeley, Berkeley, California.
Mark L RubinsteinDivision of Adolescent & Young Adult Medicine, University of California, San Francisco, San Francisco, California. Electronic address: mark.rubinstein@ucsf.edu.

Funding

Retail Environment for Tobacco and Marijuana in California: Impact on College Student UseR01CA217165 · NCI · STANFORD UNIVERSITY · PI HENRIKSEN, LISA ANNE · 2018 to 2023
$2.7M
Adolescent ENDS Use, Nicotine Metabolism and Toxicant ExposureR21DA040718 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI RUBINSTEIN, MARK L · 2016 to 2017
$436k
NCI NIH HHS R01 CA217165NIDA NIH HHS R21 DA040718
6 · The paper itself

Abstract

purposeThis study examined changes in e-cigarette and dual-use frequency, levels of nicotine exposure and e-cigarette dependence, and device and e-liquid preferences over 12 months.

methodsAdolescents (N = 173, aged 13-18 years) who reported past-month e-cigarette use and at least 10 lifetime uses were recruited from the San Francisco Bay Area. The sample was 75.1% male, 54.9% non-Hispanic White, mean age 16.6 years (standard deviation = 1.2); 26.6% reported past-month cigarette smoking at baseline (i.e., dual use). At baseline, 6-month, and 12-month follow-up, participants provided saliva samples for cotinine testing and self-reported e-cigarette use frequency, dependence, past-month smoking, product preference, and flavor preference.

resultsMost (80.3%) were still using e-cigarettes at 12 months, and daily use increased from 14.5% to 29.8%. Model testing indicated an overall increase from baseline to 12 months in frequency of e-cigarette use (F(2, 166) = 5.69, p = .004), dependence (F(2, 164) = 5.49, p = .005), and cotinine levels (F(2, 103) = 4.40, p = .038). Among those reporting only e-cigarette use at baseline, 28.8% reported combustible cigarette use during follow-up. Among those reporting dual use at baseline, 57.1% were still dual using at 12 months, 31.4% reported e-cigarette use only, and none abstained from both products. Higher nicotine delivering e-cigarette devices (i.e., Juul, mods) became more popular over time, whereas flavor preferences (i.e., fruit, mint/menthol, and candy) remained stable.

conclusionsAdolescents' e-cigarette use persisted over a 12-month period with significant increases in frequency of use, nicotine exposure, and e-cigarette dependence. Transitions from single to dual and dual to single nicotine product use were observed in approximately one in three users over the study period.

Indexed as

NicotineAdolescentCigarette SmokingCotinineElectronic Nicotine Delivery SystemsFemaleFlavoring AgentsHumansMaleSalivaSan FranciscoSelf ReportVapingCotinineFlavoring AgentsNicotineAddictionAdolescentCigarettesDependenceE-cigaretteENDSNicotine

Identifiers

PMID31122507
PMCPMC6538303

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.