ArticleParasites & vectors2019
Field data implicating Culicoides stellifer and Culicoides venustus (Diptera: Ceratopogonidae) as vectors of epizootic hemorrhagic disease virus.
Article in Parasites & vectors, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed, 66 citations in OpenAlex.
- Seventy years of hemorrhagic disease research in North America.Journal of medical entomology · 2026Review
- The Culicoides (Diptera: Ceratopogonidae) of Arkansas: a species checklist and comparison of diversity across ecoregions and habitats.Journal of medical entomology · 2026Article
- Culicoides insignis Lutz and Culicoides stellifer (Coquillett) (Diptera: Ceratopogonidae) are more active at canopy height than ground level throughout the night in Florida.Journal of medical entomology · 2026Article
- Screening for Oropouche virus in wild bird samples collected from wildlife rehabilitation centers, Florida, United States, 2021-2024.Frontiers in public health · 2026Article
- Laboratory and semifield data indicate that vector Culicoides spp. in Florida are susceptible to permethrin.Journal of medical entomology · 2025Article
- A habitat suitability analysis for three Culicoides species implicated in bluetongue virus transmission in the Southeastern United States.Medical and veterinary entomology · 2025Article
- Epizootic hemorrhagic disease virus oral infection affects midge reproduction and is vertically transmitted to offspring in Culicoides sonorensis.Scientific reports · 2025Article
- Unraveling the relationships between midge abundance and incidence, microbial communities, and soil and water properties in a protected natural tallgrass prairie.Parasites & vectors · 2025Article
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- Outlook on RNAi-Based Strategies for ControllingPathogens (Basel, Switzerland) · 2023Review
- Host Associations ofAnimals : an open access journal from MDPI · 2023Article
- Abundance and diversity of Culicoides Latreille (Diptera: Ceratopogonidae) in southern Ontario, Canada.Parasites & vectors · 2023Article
- Seroprevalence of Epizootic Hemorrhagic Disease Virus in Guangdong Cattle Farms during 2013-2017, China.Viruses · 2023Article
- Epizootic Hemorrhagic Disease Virus: Current Knowledge and Emerging Perspectives.Microorganisms · 2023Review
- Using Zoos as Sentinels for Re-Emerging Arboviruses: Vector Surveillance during an Outbreak of Epizootic Hemorrhagic Disease at the Minnesota Zoo.Pathogens (Basel, Switzerland) · 2023Article
- Assigning Culicoides larvae to species using DNA barcoding of adult females and phylogenetic associations.Parasites & vectors · 2022Article
- Article
- Species delimitation and mitonuclear discordance within a species complex of biting midges.Scientific reports · 2022Article
- A Review of the Vector Status of North AmericanCurrent tropical medicine reports · 2022Review
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEpizootic hemorrhagic disease virus (EHDV) is an Orbivirus of veterinary importance which is transmitted by biting midges of the genus Culicoides (Diptera: Ceratopogonidae) to ruminants. Culicoides sonorensis Wirth & Jones, the only confirmed vector of EHDV in the USA, is rare in the southeastern states where transmission persists, suggesting that other Culicoides species transmit EHDV in this region. The present study aimed to determine which Culicoides species transmitted EHDV in Florida and Alabama, two states in the southeastern USA. Viral RNA was detected in field-collected midges using molecular methods. These data are presented alongside data on Culicoides blood meal analysis, white-tailed deer (Odocoileus virginianus) aspiration, and seasonality to demonstrate an interaction between potential vector species and EHDV hosts.
resultsOut of 661 pools tested, 20 pools were positive for EHDV viral RNA, including six pools from Culicoides stellifer (Coquillett) and 14 pools from Culicoides venustus Hoffman. The overall infection rate was 0.06% for C. stellifer and 2.18% for C. venustus. No positive pools were identified for a further 17 species. Serotypes identified in Culicoides included EHDV-2, EHDV-6, and coinfections of EHDV-2 and EHDV-6 and were identified in similar proportions to serotypes in deer at 3 of 4 deer farms. Viral detections conducted in Alabama also identified one positive pool of C. venustus. Blood meal analysis revealed that both Culicoides species fed on white-tailed deer (verified through aspiration), fallow deer, and elk, species for which EHDV viremia has been documented. Seasonality data indicated that both species were present throughout the period in which viral transmission occurred to EHDV hosts in 2016 in addition to the 2017 epizootic.
conclusionsOur finding of EHDV positive pools of field-collected C. stellifer and C. venustus and an interaction between these species and EHDV hosts satisfy two of the four criteria for vector incrimination as set by the World Health Organization. Determining the vectors of EHDV is an important step towards developing sound strategies for the control of vector Culicoides and management of EHDV in the southeastern USA.
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